Protein Alignment gskt and Gsk3a

DIOPT Version :10

• Sequence 1: NP_733426.1
• Gene: gskt / 318552
• FlyBaseID: FBgn0046332
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_001026837.1
• Gene: Gsk3a / 606496
• MGIID: 2152453
• Length: 490
• Species: Mus musculus
• Alignment Length: 396
• Identity: 239/396 - (60%)
• Similarity: 309/396 - (78%)
• Gaps: 21/396 - (5%)

  Fly     6 KNSGLTNKVTTVVATNAFGADVMSEISYTDAKVVGNGSFGVVFQAKMVPSNEMVAIKKVLQDRRF 70
            ::||   ||||||||...|.:...|::|||.||:||||||||:||::..:.|:|||||||||:||
Mouse    95 RDSG---KVTTVVATVGQGPERSQEVAYTDIKVIGNGSFGVVYQARLAETRELVAIKKVLQDKRF 156

  Fly    71 KNRELQIMRKLRHDNIITLKWFFFSSGEKRDEVYLNLVMEFLPETLYKVERQYARAKQTLPVNFV 135
            |||||||||||.|.||:.|::||:|||||:||:|||||:|::|||:|:|.|.:.:||...|:.::
Mouse   157 KNRELQIMRKLDHCNIVRLRYFFYSSGEKKDELYLNLVLEYVPETVYRVARHFTKAKLITPIIYI 221

  Fly   136 RLYMYQLLRSMGYLHSLGFCHRDIKPQNMLLDSETGVLKLCDFGSAKQLISGEPNVSYICSRYYR 200
            ::|||||.||:.|:||.|.|||||||||:|:|.:|.|||||||||||||:.||||||||||||||
Mouse   222 KVYMYQLFRSLAYIHSQGVCHRDIKPQNLLVDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYR 286

  Fly   201 APELIFGSTDYTTKIDMWSAGCVMSELLLGQLIFPGDSGVDQIVEIVKVMGTPTSEQLHDMNPHY 265
            |||||||:||||:.||:||||||::||||||.||||||||||:|||:||:||||.||:.:|||:|
Mouse   287 APELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNY 351

  Fly   266 KQFKLPELKPHPWSKVFR-IRTPAEAIDLVSKMLIYSPNARVSPLMGCAHPFFDELRQDPHQQLP 329
            .:||.|::|.|||:|||: .:||.|||.|.|.:|.|:|::|:|||..|||.||||||: ...|||
Mouse   352 TEFKFPQIKAHPWTKVFKSSKTPPEAIALCSSLLEYTPSSRLSPLEACAHSFFDELRR-LGAQLP 415

  Fly   330 NGRSLPPLFNFTDYEKTIEPDTMPLLLPRAQGSSTTKEPSAAHRNRNTAGEESPRKTEDSQKPAT 394
            |.|.|||||||:..|.:|:|....:|:|             .|. |:.||..||..|  |..|::
Mouse   416 NDRPLPPLFNFSPGELSIQPSLNAILIP-------------PHL-RSPAGPASPLTT--SYNPSS 464

  Fly   395 AALSKS 400
            .||:::
Mouse   465 QALTEA 470

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gskt	NP_733426.1	STKc_GSK3	30..320	CDD:271039	197/290 (68%)
Gsk3a	NP_001026837.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..97		0/1 (0%)
		STKc_GSK3	114..407	CDD:271039	197/292 (67%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	451..490		8/22 (36%)