Protein Alignment gskt and GSK3B

DIOPT Version :9

• Sequence 1: NP_733426.1
• Gene: gskt / 318552
• FlyBaseID: FBgn0046332
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_002084.2
• Gene: GSK3B / 2932
• HGNCID: 4617
• Length: 433
• Species: Homo sapiens
• Alignment Length: 405
• Identity: 252/405 - (62%)
• Similarity: 312/405 - (77%)
• Gaps: 23/405 - (5%)

  Fly    12 NKVTTVVATNAFGADVMSEISYTDAKVVGNGSFGVVFQAKMVPSNEMVAIKKVLQDRRFKNRELQ 76
            :||||||||...|.|...|:||||.||:||||||||:|||:..|.|:|||||||||:||||||||
Human    35 SKVTTVVATPGQGPDRPQEVSYTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNRELQ 99

  Fly    77 IMRKLRHDNIITLKWFFFSSGEKRDEVYLNLVMEFLPETLYKVERQYARAKQTLPVNFVRLYMYQ 141
            |||||.|.||:.|::||:|||||:||||||||::::|||:|:|.|.|:||||||||.:|:|||||
Human   100 IMRKLDHCNIVRLRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQ 164

  Fly   142 LLRSMGYLHSLGFCHRDIKPQNMLLDSETGVLKLCDFGSAKQLISGEPNVSYICSRYYRAPELIF 206
            |.||:.|:||.|.|||||||||:|||.:|.|||||||||||||:.||||||||||||||||||||
Human   165 LFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIF 229

  Fly   207 GSTDYTTKIDMWSAGCVMSELLLGQLIFPGDSGVDQIVEIVKVMGTPTSEQLHDMNPHYKQFKLP 271
            |:||||:.||:||||||::||||||.||||||||||:|||:||:||||.||:.:|||:|.:||.|
Human   230 GATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFKFP 294

  Fly   272 ELKPHPWSK-------------VFRIRTPAEAIDLVSKMLIYSPNARVSPLMGCAHPFFDELRQD 323
            ::|.|||:|             |||.|||.|||.|.|::|.|:|.||::||..|||.|||||| |
Human   295 QIKAHPWTKDSSGTGHFTSGVRVFRPRTPPEAIALCSRLLEYTPTARLTPLEACAHSFFDELR-D 358

  Fly   324 PHQQLPNGRSLPPLFNFTDYEKTIEPDTMPLLLP---RAQGSSTTKEPSAAHRNRNTAGEESPRK 385
            |:.:|||||..|.|||||..|.:..|....:|:|   |.|.:::|...:.|..:.|| |:..
Human   359 PNVKLPNGRDTPALFNFTTQELSSNPPLATILIPPHARIQAAASTPTNATAASDANT-GDRG--- 419

  Fly   386 TEDSQKPATAALSKS 400
              .:...|:|:.|.|
Human   420 --QTNNAASASASNS 432

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gskt	NP_733426.1	STKc_GSK3	30..320	CDD:271039	211/302 (70%)
		S_TKc	33..317	CDD:214567	206/296 (70%)
GSK3B	NP_002084.2	STKc_GSK3	51..356	CDD:271039	211/304 (69%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165147079
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0658
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S377
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D990896at2759
OrthoFinder	1	1.000	-	-		FOG0000635
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100482
Panther	1	1.100	-	-	O	PTHR24057
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X378
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	11	10.660