DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12056 and cyb5d2

DIOPT Version :9

Sequence 1:	NP_572535.1	Gene:	CG12056 / 31855	FlyBaseID:	FBgn0030099	Length:	287	Species:	Drosophila melanogaster
Sequence 2:	NP_001016154.1	Gene:	cyb5d2 / 548908	XenbaseID:	XB-GENE-981419	Length:	273	Species:	Xenopus tropicalis

Alignment Length:	231	Identity:	89/231 - (38%)
Similarity:	131/231 - (56%)	Gaps:	9/231 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    61 GTLFTPAELAKFNGEEEGRPLYLALLGSVFDVSRGIKHYGSGCSYNFFVGRDASVSFISGDFETY 125
            |.|.:..||:.::|......:|||:||.||||.:|.||||.|.||:||.|:|||.::::|||.
Frog    44 GRLMSKEELSVYDGGPGSSGIYLAILGQVFDVHKGSKHYGPGGSYSFFAGKDASRAYMTGDFT-- 106

  Fly   126 DPETADDVLTLKPDDLIGLAGWRDFYQKDYVYKGRVIGRFYDEKGALTTYHHKFLELLEQARDAK 190
            :....|||..|.|..::.|..|..|||::|:..|::.||||||.|..|......|::::.....|
Frog   107 EKGLVDDVTELSPLQMLHLHNWLSFYQQNYITIGKLTGRFYDESGNPTKALEDALKVIDIGLKLK 171

  Fly   191 RQVEELRARYPGCNIEWSEERGTRVWCTTTSGDGKERSWIGYPRKLYSRGNKSFQCACV-----P 250
            .:.||...::|.||.|||.| ..||||:..|| |.:|.|:|.|||:|:.|...::|.||     |
Frog   172 EEREEENKQFPPCNSEWSSE-SKRVWCSKNSG-GIQRDWVGVPRKMYTAGTNGYRCVCVRNFGPP 234

  Fly   251 DAELDEIDAGGKVAHGDAMLKPYDNCEPQARECFYR 286
            ..:.|..:...:....:.||..|::|.|....||.:
Frog   235 SEQPDSTEHNDRGDLDNPMLHEYEDCNPLFEWCFLK 270

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12056	NP_572535.1	Cyt-b5	63..>117	CDD:278597	27/53 (51%)
cyb5d2	NP_001016154.1	Cyt-b5	48..>109	CDD:365921	29/62 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	102	1.000	Domainoid score	I6799
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H14701
Inparanoid	1	1.050	174	1.000	Inparanoid score	I3959
OMA	1	1.010	-	-		QHG59781
OrthoDB	1	1.010	-	-		D1355837at2759
OrthoFinder	1	1.000	-	-		FOG0006068
OrthoInspector	1	1.000	-	-		oto102279
Panther	1	1.100	-	-	LDO	PTHR10281
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2676
SonicParanoid	1	1.000	-	-		X4364
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	12	12.110