DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12056 and PGRMC1

DIOPT Version :9

Sequence 1:	NP_572535.1	Gene:	CG12056 / 31855	FlyBaseID:	FBgn0030099	Length:	287	Species:	Drosophila melanogaster
Sequence 2:	NP_006658.1	Gene:	PGRMC1 / 10857	HGNCID:	16090	Length:	195	Species:	Homo sapiens

Alignment Length:	127	Identity:	41/127 - (32%)
Similarity:	62/127 - (48%)	Gaps:	13/127 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    64 FTPAELAKFNGEEEGRPLYLALLGSVFDVSRGIKHYGSGCSYNFFVGRDAS--VSFISGDFETYD 126
            ||||||.:|:|.::.| :.:|:.|.||||::|.|.||....|..|.|||||  ::....|.|...
Human    73 FTPAELRRFDGVQDPR-ILMAINGKVFDVTKGRKFYGPEGPYGVFAGRDASRGLATFCLDKEALK 136

  Fly   127 PETADDVLTLKPDDLIGLAGWRDFYQKDYVYKGRVIGRFYDEKGALTTYHHKFLELLEQARD 188
            .| .||:..|.......|:.|    :..:.:|...:|:...|....|.|..:     |:.:|
Human   137 DE-YDDLSDLTAAQQETLSDW----ESQFTFKYHHVGKLLKEGEEPTVYSDE-----EEPKD 188

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12056	NP_572535.1	Cyt-b5	63..>117	CDD:278597	26/54 (48%)
PGRMC1	NP_006658.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	51..71
		Cyt-b5	74..137	CDD:306642	27/63 (43%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	173..195		5/21 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1110
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810