DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Zpr1 and zpr1

DIOPT Version :9

Sequence 1:	NP_572532.1	Gene:	Zpr1 / 31851	FlyBaseID:	FBgn0030096	Length:	457	Species:	Drosophila melanogaster
Sequence 2:	NP_001017134.1	Gene:	zpr1 / 549888	XenbaseID:	XB-GENE-941928	Length:	446	Species:	Xenopus tropicalis

Alignment Length:	438	Identity:	210/438 - (47%)
Similarity:	299/438 - (68%)	Gaps:	10/438 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 IFREINAE-QTDEIVEVESACMNCFETGVTRLLPTKIPFFREVVLMSFKCDHCGHINNEMQSASE 87
            :||:|:|| :..:..|:||.||||:..|:||||.|::|||:|:::.||.||.||..|.|:|||..
Frog    15 LFRDISAEDEEQQPAEIESLCMNCYHNGLTRLLLTRVPFFKEIIVSSFTCDSCGWSNTEIQSAGR 79

  Fly    88 IQKSGIRIELRVQSVADLNRRVVRSDNSSISIPEIELEIPVQSQKGEVTTVEGIIERTIAGLSQD 152
            ||:.|::..|.|::..|:||.|:::|.:.:.|||::.|||..||||.:||:||||||||.||.|:
Frog    80 IQEQGVQYSLSVRNKQDVNREVIKTDYAKVQIPELDFEIPACSQKGALTTIEGIIERTIVGLQQE 144

  Fly   153 QEKRRIDHPETAASIEKYIERLHRLKEVTTPFQVLLEDISGNSFIENPLAPAADPQLKTSYFTRS 217
            |..||.::...||.::::|.:|.|||:....|..:::|.|||||:|||.||..|..|..:.:.|:
Frog   145 QSLRRAENESIAAKVDEFIIKLQRLKDGEDQFTFIIDDPSGNSFVENPFAPQKDEALLVTRYKRT 209

  Fly   218 QQQNEQLGLYEQNHEEQHLLKPIAEDSWPIENLHGEVLQFPTNCPSCQAPCETNMKLTNIPHFKE 282
            .:|:..|||...:..::...||:...    |.|..||||||||||.|..|.:|||||..||||||
Frog   210 PEQDVLLGLESSSASQKQEEKPMPTS----EELRDEVLQFPTNCPECNVPAKTNMKLVQIPHFKE 270

  Fly   283 VVIMATVCGACGHKTNEVKSGGGVEAQGVRFRVQIASREDLTRDVLKSETCSMSIPELDLEVGPH 347
            |:||||.|.:|||:||||||||.:|..|.|..:.|....||||||||||||.:|:|||:.|:|..
Frog   271 VIIMATNCDSCGHRTNEVKSGGAIEPLGTRITLHITDLSDLTRDVLKSETCGISVPELEFELGMG 335

  Fly   348 ALCGRFTTVEGLLVAMRD-QLDGTLF--HDSADDATKQQMQRFLDTFEDVMNLKRVITLVLEDPA 409
            ||.|:|||:||||..::| .:|...|  .||:....:::::.|....:.::........:|:|||
Frog   336 ALGGKFTTLEGLLKDIKDLVVDKNPFTLGDSSSSDRREKLEDFGRKIDQILEGHLKAHFILDDPA 400

  Fly   410 GNTYVQSLSDDDSEPDDKLTVERYDRSYEDNEDLGLNDMKTEGYEEKA 457
            ||:|:|::...:.:|:.|  ||:|:|::|.||||||||||||||||||
Frog   401 GNSYLQNVYAPEEDPEMK--VEKYERTFEQNEDLGLNDMKTEGYEEKA 446

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Zpr1	NP_572532.1	Zpr1	41..199	CDD:128949	76/157 (48%)
Zpr1	NP_572532.1	Zpr1	259..416	CDD:128949	79/159 (50%)
zpr1	NP_001017134.1	zf-ZPR1	33..190	CDD:377027	76/156 (49%)
zpr1	NP_001017134.1	zf-ZPR1	247..406	CDD:377027	79/158 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	171	1.000	Domainoid score	I3714
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2900
Inparanoid	1	1.050	421	1.000	Inparanoid score	I1753
OMA	1	1.010	-	-		QHG54073
OrthoDB	1	1.010	-	-		D250130at33208
OrthoFinder	1	1.000	-	-		FOG0004365
OrthoInspector	1	1.000	-	-		oto104955
Panther	1	1.100	-	-	LDO	PTHR10876
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2015
SonicParanoid	1	1.000	-	-		X3087
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	12	12.110