DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Zpr1 and Zpr1

DIOPT Version :9

Sequence 1:	NP_572532.1	Gene:	Zpr1 / 31851	FlyBaseID:	FBgn0030096	Length:	457	Species:	Drosophila melanogaster
Sequence 2:	NP_001131118.1	Gene:	Zpr1 / 500989	RGDID:	1562173	Length:	459	Species:	Rattus norvegicus

Alignment Length:	454	Identity:	218/454 - (48%)
Similarity:	296/454 - (65%)	Gaps:	23/454 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 PPESAGNIRPE--------PIFREINAE-QTDEIVEVESACMNCFETGVTRLLPTKIPFFREVVL 67
            ||.:|....|.        |:||.::|| :..:..|:||.||||:..|.||||.||||||||:::
  Rat    11 PPGAAVGPSPTAAALSDTGPLFRPLSAEDEEQQPTEIESLCMNCYRNGTTRLLLTKIPFFREIIV 75

  Fly    68 MSFKCDHCGHINNEMQSASEIQKSGIRIELRVQSVADLNRRVVRSDNSSISIPEIELEIPVQSQK 132
            .||.|:|||..|.|:|||..||..|:|..|.|:...|:||.||::|:::..|||::.|||..|||
  Rat    76 SSFSCEHCGWNNTEIQSAGRIQDQGVRYTLTVKGQEDMNREVVKTDSATTRIPELDFEIPAFSQK 140

  Fly   133 GEVTTVEGIIERTIAGLSQDQEKRRIDHPETAASIEKYIERLHRLKEVTTPFQVLLEDISGNSFI 197
            |.:|||||:|.|.|.||.|||..||......|..|:::|.:|..||::.:||.::::|.|||||:
  Rat   141 GALTTVEGLISRAILGLEQDQPTRRAMEGAIAERIDEFIGKLKDLKQMASPFTLIIDDPSGNSFV 205

  Fly   198 ENPLAPAADPQLKTSYFTRSQQQNEQLGLYEQNHEEQHLLKPIAEDSWPIENLHGEVLQFPTNCP 262
            |||.||..|..|..:|:.|:.||.|.|||..:..||:      :|:    |:|..|||||.||||
  Rat   206 ENPHAPQKDSALVITYYDRTPQQAEMLGLQAEAPEEK------SEE----EDLRNEVLQFNTNCP 260

  Fly   263 SCQAPCETNMKLTNIPHFKEVVIMATVCGACGHKTNEVKSGGGVEAQGVRFRVQIASREDLTRDV 327
            .|.||.:|||||..|||||||:||||.|..|||:||||||||.||..|.|..:.|....|:|||:
  Rat   261 ECNAPAQTNMKLVQIPHFKEVIIMATNCERCGHRTNEVKSGGAVEPLGTRITLHITDPSDMTRDL 325

  Fly   328 LKSETCSMSIPELDLEVGPHALCGRFTTVEGLLVAMRDQLDGTLF--HDSADDATKQQMQRFLDT 390
            |||||||:.||||:.|:|...|.|:|||:||||..:|:.:....|  .||::....:::|.|...
  Rat   326 LKSETCSVEIPELEFELGMAVLGGKFTTLEGLLKDIRELVTKNPFTLGDSSNPDQSEKLQEFSQK 390

  Fly   391 FEDVMNLKRVITLVLEDPAGNTYVQSLSDDDSEPDDKLTVERYDRSYEDNEDLGLNDMKTEGYE 454
            ...::..|.....::.|||||:|:|::...:.:|:.|  ||||.||::.||:||||||||||||
  Rat   391 LGQIIEGKMKAHFIMNDPAGNSYLQNVYAPEDDPEMK--VERYKRSFDQNEELGLNDMKTEGYE 452

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Zpr1	NP_572532.1	Zpr1	41..199	CDD:128949	80/157 (51%)
Zpr1	NP_572532.1	Zpr1	259..416	CDD:128949	79/158 (50%)
Zpr1	NP_001131118.1	zf-ZPR1	49..206	CDD:281375	80/156 (51%)
Zpr1	NP_001131118.1	Zpr1	257..416	CDD:128949	80/160 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166353344
Domainoid	1	1.000	171	1.000	Domainoid score	I3650
eggNOG	1	0.900	-	-		E1_COG1779
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2900
Inparanoid	1	1.050	418	1.000	Inparanoid score	I1753
OMA	1	1.010	-	-		QHG54073
OrthoDB	1	1.010	-	-		D250130at33208
OrthoFinder	1	1.000	-	-		FOG0004365
OrthoInspector	1	1.000	-	-		oto98261
orthoMCL	1	0.900	-	-		OOG6_101443
Panther	1	1.100	-	-	LDO	PTHR10876
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3087
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.770