Protein Alignment Ost48 and DDOST

DIOPT Version :10

• Sequence 1: NP_511096.2
• Gene: Ost48 / 31849
• FlyBaseID: FBgn0014868
• Length: 449
• Species: Drosophila melanogaster
• Sequence 2: NP_005207.3
• Gene: DDOST / 1650
• HGNCID: 2728
• Length: 439
• Species: Homo sapiens
• Alignment Length: 437
• Identity: 263/437 - (60%)
• Similarity: 334/437 - (76%)
• Gaps: 14/437 - (3%)

  Fly     1 MMWKALLIAVLAIAHCQAVLETDANTLVLLDNLAIRETHSIFFKSLQDRGFKLTYKLADDSSLLL 65
            :.|  ||:.:|.     ||..:...||||||||.:|||||:||:||:||||:||:|.|||.||.|
Human    12 LFW--LLLPLLG-----AVCASGPRTLVLLDNLNVRETHSLFFRSLKDRGFELTFKTADDPSLSL 69

  Fly    66 SKYGEYLYKNVIIFAPSVEEFGGDVSVERLAQFVDDGGNVLVAGSEKSGDALREFASECGFELDE 130
            .||||:||.|:|||:||||:|||:::||.::.|:|.||:||||.|...||.|||..||||.|.||
Human    70 IKYGEFLYDNLIIFSPSVEDFGGNINVETISAFIDGGGSVLVAASSDIGDPLRELGSECGIEFDE 134

  Fly   131 ENAAVIDHLHYDVSDAGEHTTILTSAKNLIQADTIVGKANRQADAAPLLYRGTGLIADKENPLVL 195
            |..|||||.:||:||.|:||.|:...:||::|.|||||::..    |:|:||.|::||.:|||||
Human   135 EKTAVIDHHNYDISDLGQHTLIVADTENLLKAPTIVGKSSLN----PILFRGVGMVADPDNPLVL 195

  Fly   196 KLLTAESTAYSYNPEASVSDYPHAVGRGTLLIAALQARNNARVVFSGSLLFFSDESFTTAVQYAQ 260
            .:||..||:||:.|:..::.||||||:.|||||.|||||||||:|||||.||||..|.:|||.|.
Human   196 DILTGSSTSYSFFPDKPITQYPHAVGKNTLLIAGLQARNNARVIFSGSLDFFSDSFFNSAVQKAA 260

  Fly   261 SG-VFHKLAGNRDVAESISKWVFGETGRLRVASVQHHKEGELLPPDQAYTITDPVVYTIGIEELV 324
            .| ..:...||.::|.::|:|||.|.|.|||..|.||:.||..||: |||:||.|.|:|.|::|.
Human   261 PGSQRYSQTGNYELAVALSRWVFKEEGVLRVGPVSHHRVGETAPPN-AYTVTDLVEYSIVIQQLS 324

  Fly   325 QGEWRAFKASDIQLEFVRIDPFVRTYLKQTNTGAYQAKFKIPDVYGVYQFKVDYNRVGYTHLYST 389
            .|:|..|...|||||||||||||||:||:.. |.|..:||:||||||:||||||||:|||||||:
Human   325 NGKWVPFDGDDIQLEFVRIDPFVRTFLKKKG-GKYSVQFKLPDVYGVFQFKVDYNRLGYTHLYSS 388

  Fly   390 TQVSVRPLEHTQYERFIPSAFPYYTSAFSMMIGVFVFSFVFLHFKDE 436
            ||||||||:|||||||||||:|||.||||||:|:|:||.||||.|::
Human   389 TQVSVRPLQHTQYERFIPSAYPYYASAFSMMLGLFIFSIVFLHMKEK 435

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ost48	NP_511096.2	DDOST_48kD	25..434	CDD:460890	256/409 (63%)
DDOST	NP_005207.3	DDOST_48kD	29..433	CDD:460890	256/409 (63%)