DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ost48 and ddost

DIOPT Version :9

Sequence 1:	NP_511096.2	Gene:	Ost48 / 31849	FlyBaseID:	FBgn0014868	Length:	449	Species:	Drosophila melanogaster
Sequence 2:	NP_001120481.1	Gene:	ddost / 100145597	XenbaseID:	XB-GENE-5784936	Length:	437	Species:	Xenopus tropicalis

Alignment Length:	437	Identity:	258/437 - (59%)
Similarity:	332/437 - (75%)	Gaps:	11/437 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 ALLIAVLAI-AHCQAV---LETDANTLVLLDNLAIRETHSIFFKSLQDRGFKLTYKLADDSSLLL 65
            :|.::||.: |.|..:   |.....|||||:|:.:|||||:||:||.||||.|:::.|||.||.|
Frog     3 SLRVSVLLVAASCLLLGSGLRAGPRTLVLLENINLRETHSLFFRSLSDRGFDLSFRTADDPSLSL 67

  Fly    66 SKYGEYLYKNVIIFAPSVEEFGGDVSVERLAQFVDDGGNVLVAGSEKSGDALREFASECGFELDE 130
            .||||:||.|:|||:||||:|||::::|.::.|:|.||:||||.|...||.|||..||||.|.||
Frog    68 IKYGEFLYDNLIIFSPSVEDFGGNINIETISSFIDGGGSVLVAASSDIGDPLRELGSECGIEFDE 132

  Fly   131 ENAAVIDHLHYDVSDAGEHTTILTSAKNLIQADTIVGKANRQADAAPLLYRGTGLIADKENPLVL 195
            :..|||||.:||:||.|:|:.|:..:::|::|.|||||    |...|:|:||.|::||.:|||||
Frog   133 DKTAVIDHHNYDISDPGQHSLIVADSESLLKAPTIVGK----APLNPILFRGVGMVADPDNPLVL 193

  Fly   196 KLLTAESTAYSYNPEASVSDYPHAVGRGTLLIAALQARNNARVVFSGSLLFFSDESFTTAVQYAQ 260
            .:||..||:||:.|:..::.||||||:.|||||.||||||||||||||:.||||..|.:|||.|.
Frog   194 DILTGSSTSYSFFPDKPITQYPHAVGKNTLLIAGLQARNNARVVFSGSMDFFSDAFFNSAVQKAA 258

  Fly   261 SGV-FHKLAGNRDVAESISKWVFGETGRLRVASVQHHKEGELLPPDQAYTITDPVVYTIGIEELV 324
            .|. .:...||.::|.::|:|||.|.|.|||..|.||:.||..|| .|||:||.|.|:|.||:|.
Frog   259 GGSNRYAKTGNYELAVALSRWVFKEEGVLRVGQVSHHRVGESSPP-SAYTVTDLVEYSIVIEQLS 322

  Fly   325 QGEWRAFKASDIQLEFVRIDPFVRTYLKQTNTGAYQAKFKIPDVYGVYQFKVDYNRVGYTHLYST 389
            .|:|..|...|||||||||||||||:||: |.|.|..:||:||||||:||||||||:||||||||
Frog   323 NGKWVPFDGDDIQLEFVRIDPFVRTFLKK-NGGKYSVQFKLPDVYGVFQFKVDYNRLGYTHLYST 386

  Fly   390 TQVSVRPLEHTQYERFIPSAFPYYTSAFSMMIGVFVFSFVFLHFKDE 436
            ||||||||:|||||||||||:|||.||||:|.|:|:||.||||.|::
Frog   387 TQVSVRPLQHTQYERFIPSAYPYYASAFSVMFGLFIFSIVFLHMKEK 433

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ost48	NP_511096.2	DDOST_48kD	27..437	CDD:281356	251/411 (61%)
ddost	NP_001120481.1	DDOST_48kD	28..436	CDD:367455	252/412 (61%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	514	1.000	Domainoid score	I316
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H3821
Inparanoid	1	1.050	515	1.000	Inparanoid score	I1270
OMA	1	1.010	-	-		QHG54376
OrthoDB	1	1.010	-	-		D308610at33208
OrthoFinder	1	1.000	-	-		FOG0004192
OrthoInspector	1	1.000	-	-		otm48431
Panther	1	1.100	-	-	LDO	PTHR10830
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R878
SonicParanoid	1	1.000	-	-		X2938
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	13	13.110