DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment His3.3B and H3-3A

DIOPT Version :9

Sequence 1:	NP_001259374.1	Gene:	His3.3B / 31848	FlyBaseID:	FBgn0004828	Length:	136	Species:	Drosophila melanogaster
Sequence 2:	NP_001365972.1	Gene:	H3-3A / 3020	HGNCID:	4764	Length:	136	Species:	Homo sapiens

Alignment Length:	136	Identity:	136/136 - (100%)
Similarity:	136/136 - (100%)	Gaps:	0/136 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MARTKQTARKSTGGKAPRKQLATKAARKSAPSTGGVKKPHRYRPGTVALREIRRYQKSTELLIRK 65
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Human     1 MARTKQTARKSTGGKAPRKQLATKAARKSAPSTGGVKKPHRYRPGTVALREIRRYQKSTELLIRK 65

  Fly    66 LPFQRLVREIAQDFKTDLRFQSAAIGALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARR 130
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Human    66 LPFQRLVREIAQDFKTDLRFQSAAIGALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARR 130

  Fly   131 IRGERA 136
            ||||||
Human   131 IRGERA 136

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
His3.3B	NP_001259374.1	PTZ00018	1..136	CDD:185400	134/134 (100%)
H3-3A	NP_001365972.1	PTZ00018	1..136	CDD:185400	134/134 (100%)
H3-3A	NP_001365972.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..43		41/41 (100%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153881
Domainoid	1	1.000	257	1.000	Domainoid score	I2023
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	265	1.000	Inparanoid score	I3059
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54047
OrthoDB	1	1.010	-	-		D476949at33208
OrthoFinder	1	1.000	-	-		FOG0000188
OrthoInspector	1	1.000	-	-		oto90732
orthoMCL	1	0.900	-	-		OOG6_100119
Panther	1	1.100	-	-	LDO	PTHR11426
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X183
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	12	11.910