DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Bap111 and smarce1

DIOPT Version :9

Sequence 1:	NP_572530.1	Gene:	Bap111 / 31846	FlyBaseID:	FBgn0030093	Length:	749	Species:	Drosophila melanogaster
Sequence 2:	XP_005164046.1	Gene:	smarce1 / 322248	ZFINID:	ZDB-GENE-030131-967	Length:	426	Species:	Danio rerio

Alignment Length:	411	Identity:	177/411 - (43%)
Similarity:	240/411 - (58%)	Gaps:	68/411 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    55 HSNY---GNPAFTPQKVTKSSSSKNQNES--RLPKPPKPPEKPILPYMRY----SKRVWDSVKAK 110
            ::||   |||         |.:::..|.|  .:|||||||:||::|||||    |::|||.|||.
Zfish    36 YNNYRLGGNP---------SGNNRVMNSSGITVPKPPKPPDKPLMPYMRYSRKVSRKVWDQVKAS 91

  Fly   111 HPELKLWELGKKIGAMWKLLPEDEKTEFIDEYEAEKLEYEKSLKAYHQTPAYQAYMSAKSKVKTD 175
            :|:|||||:||.||.||:.|.::||.::::||||||:||..||||||.:|||.||::||::.:..
Zfish    92 NPDLKLWEIGKIIGGMWRDLTDEEKQDYLNEYEAEKIEYNDSLKAYHNSPAYLAYVNAKNRAEAA 156

  Fly   176 VDMHETPSRGGGSKSQHERRID-------IQPAEDEDDQDEGYTTKHLAYARYLHNHRLINEIFS 233
            :   |..||      |.:.|:|       ||||||.||.|:|::.||.|.||:..|||||::|.|
Zfish   157 L---EEESR------QRQSRLDKGEPYMSIQPAEDPDDYDDGFSMKHTAAARFQRNHRLISDILS 212

  Fly   234 EAVVPDVRSVVTTTRMQVLKRQVSSLTMHQTKLEAELQQMEEKFEAKKQRMVESSEAFQEELKRH 298
            |.|||||||||||.|||||||||.||.:||.||||||.|:|::.:.||:|.:||:::|..||||.
Zfish   213 EVVVPDVRSVVTTARMQVLKRQVQSLMVHQRKLEAELLQIEDRHQEKKRRFLESTDSFNNELKRL 277

  Fly   299 C--KPAVDEETF-------QKMVLRMYEDIKRDRQRLDEPNANANSAANPAAAAATAAAAPVTRS 354
            |  |..||.|..       ::...|..|:  |:|:..::....|.....||:|.|.|.....:.|
Zfish   278 CGLKVEVDMEKLAAEMAAAEEAARRRAEE--REREAAEQVERAAQEEQQPASAQANANTEQTSAS 340

  Fly   355 EEAVKPPTQPGQPAATP-----------AGQEPASAVPA---PAAPPKETPPAVKPATLNPT-PS 404
            |      |:.|:...||           ..||.....||   .||.|:....|....|.:.| ||
Zfish   341 E------TKDGEDKPTPMETESLAETSEGSQEAEQGTPAAGEKAAQPEPAEGATDEGTSDSTAPS 399

  Fly   405 STPTPAPAVHVHETASKTDPE 425
            .:.:..||  .|:|||...||
Zfish   400 ESSSGPPA--EHQTASDNTPE 418

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Bap111	NP_572530.1	HMGB-UBF_HMG-box	95..154	CDD:238686	36/62 (58%)
smarce1	XP_005164046.1	HMGB-UBF_HMG-box	70..135	CDD:238686	36/64 (56%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170579020
Domainoid	1	1.000	106	1.000	Domainoid score	I6561
eggNOG	1	0.900	-	-		E1_KOG4715
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	296	1.000	Inparanoid score	I2722
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0006618
OrthoInspector	1	1.000	-	-		oto40223
orthoMCL	1	0.900	-	-		OOG6_108132
Panther	1	1.100	-	-	LDO	PTHR46232
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4242
SonicParanoid	1	1.000	-	-		X4858
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	12	11.780