Protein Alignment fh and FXN

DIOPT Version :9

• Sequence 1: NP_511094.1
• Gene: fh / 31845
• FlyBaseID: FBgn0030092
• Length: 190
• Species: Drosophila melanogaster
• Sequence 2: NP_000135.2
• Gene: FXN / 2395
• HGNCID: 3951
• Length: 210
• Species: Homo sapiens
• Alignment Length: 185
• Identity: 77/185 - (41%)
• Similarity: 105/185 - (56%)
• Gaps: 17/185 - (9%)

  Fly     4 GRLMVRSIVGRACLATMGRWSKPQAHASQVILPSTPAIAAVAIQCEEFTANRRLFSSQIETESTL 68
            ||..:|:.:...|  |..|.|..|...:|:......::         :..|.|. |..:....:|
Human    38 GRRGLRTDIDATC--TPRRASSNQRGLNQIWNVKKQSV---------YLMNLRK-SGTLGHPGSL 90

  Fly    69 DGATYERVCSDTLDALCDYFEELTENASELQGTDVAYSDGVLTVNLGGQHGTYVINRQTPNKQIW 133
            |..||||:..:|||:|.::||:|.:.....:..||::..|||||.|||..||||||:||||||||
Human    91 DETTYERLAEETLDSLAEFFEDLADKPYTFEDYDVSFGSGVLTVKLGGDLGTYVINKQTPNKQIW 155

  Fly   134 LSSPTSGPKRYDFVGTVAAGRWIYKHSGQSLHELLQQEIPGILKSQSVDFLRLPY 188
            ||||:|||||||:.|.    .|:|.|.|.||||||..|:...||:: :|...|.|
Human   156 LSSPSSGPKRYDWTGK----NWVYSHDGVSLHELLAAELTKALKTK-LDLSSLAY 205

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fh	NP_511094.1	mito_frataxin	72..173	CDD:132463	58/100 (58%)
FXN	NP_000135.2	mito_frataxin	94..192	CDD:132463	58/101 (57%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165148090
Domainoid	1	1.000	128	1.000	Domainoid score	I5341
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	133	1.000	Inparanoid score	I4617
Isobase	1	0.950	-	0	Normalized mean entropy	S1580
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1372185at2759
OrthoFinder	1	1.000	-	-		FOG0004275
OrthoInspector	1	1.000	-	-		oto91437
orthoMCL	1	0.900	-	-		OOG6_102217
Panther	1	1.100	-	-	LDO	PTHR16821
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3009
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	12	11.850