DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AP-1gamma and AT1G31730

DIOPT Version :9

Sequence 1:	NP_788891.2	Gene:	AP-1gamma / 31842	FlyBaseID:	FBgn0030089	Length:	982	Species:	Drosophila melanogaster
Sequence 2:	NP_174454.2	Gene:	AT1G31730 / 840060	AraportID:	AT1G31730	Length:	938	Species:	Arabidopsis thaliana

Alignment Length:	945	Identity:	218/945 - (23%)
Similarity:	391/945 - (41%)	Gaps:	165/945 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    50 DLIRQIRAARTAAEERAVVNKECAYIRSTFREEDSVWRCRN--IAKLLYIHMLGYPAHFGQLECL 112
            ||::.|..||:.|||..:|..|...::....|.|...|...  |.:|:||.|||:.|.||.:..:
plant    27 DLVKSIGEARSKAEEDRIVLSEVDILKRRLLEPDIPKRKMKEYIIRLVYIEMLGHDASFGYIYAV 91

  Fly   113 KLTASTRFTDKRIGYLGAMLLLDERQDVHLLITNCLKNDLNSSTQFVVGLALCTLGAIASPEMAR 177
            |:|.......||.|||...|.|:|..|:.:||.|.::.||.|....||..||..:..:.:.|...
plant    92 KMTHDDNLLLKRTGYLAVTLFLNEDHDLIILIVNTIQKDLRSDNYLVVCAALNAICRLINEETIP 156

  Fly   178 DLASEVERLMKSPNTYIRKKATLCAFRVIRRVPELMEIFLPATRSLLSEKNHGILITGVTLITEM 242
            .:..:|..|:......:||||.:...|..|:.|..:...:...|..|.:.:.|::  |.||....
plant   157 AVLPQVVELLNHQKEAVRKKAIMALHRFHRKSPSSVSHLVSNFRKRLCDNDPGVM--GATLCPLF 219

  Fly   243 CENSSDTLMHFKKDSGNREIVPNLVRILKNLILGGYSPEHDVSGVSDPFLQVKILRLLRILGHND 307
            ...|.|.       :..:::|.:.|.|||.:........:|...:..||:|:|:|:::.:||..|
plant   220 DLISEDV-------NSYKDLVSSFVSILKQVTERRLPKSYDYHQMPAPFIQIKLLKIMALLGSGD 277

  Fly   308 PDASEAMNDILAQVATNTETSKNVGNTILYETVLSIMDIRSEGGLRVLAVNILGRFLLNSDKNIR 372
            .:||:.|:.:|..:....::|.|:||.||||.:..|..|.....|...|.:.:.:||.:...|::
plant   278 KNASDIMSMVLGDLFRKCDSSTNIGNAILYECIRCISCILPNPKLLEAAADAISKFLKSDSHNLK 342

  Fly   373 YVALNTLLRTVHADTSAVQRHRTTILECLKDPDVSIRRRAMELSFALINAQNIRTMTKELLLFLE 437
            |:.::.|.|.:.......::|:..:::||:|||.:::|:..||.:.:..:.|:..:...::.::.
plant   343 YMGIDGLGRLIKISPDIAEQHQLAVIDCLEDPDDTLKRKTFELLYKMTKSSNVEVIVDRMIDYMI 407

  Fly   438 KA-DAEFKAQCSSGMILAAERYSPTTRWHLDTQLSVLIAAGNYVRDDVVSSTIQLVSSSPVPEQT 501
            .. |..:|.:.:|..:..||:::|:.:|.:.....|...||:.|...|..:.::|::.....:..
plant   408 SINDNHYKTEIASRCVELAEQFAPSNQWFIQIMNKVFEHAGDLVNIKVAHNLMRLIAEGFGEDDD 472

  Fly   502 YITNRFWES-----LQVANHCEDKQP--LLQVAVWAIGEYG----------------DLFMYGAN 543
            ...::...|     ||:.:  |.|.|  .|||..|.:||||                |:....::
plant   473 DADSKLRLSAVESYLQLIS--EPKLPSLFLQVISWVLGEYGTADGKYSASYISGKLCDVADAYSS 535

  Fly   544 EDEFERPTESDLIAVY-YKFLTSAQVSTTSKQYALVS--LAKLSTRLQQCVEEIQALITSFGSHL 605
            ::..:....|.|:.:| ::..:..:|....:..:|:.  ||..||.|||...|:|||:.
plant   536 DETVKGYAVSALMKIYAFEIASGRKVDVLPECQSLIEELLASHSTDLQQRAYELQALLA------ 594

  Fly   606 NVDLQQRGVEFTQLFGHYKHLRPPLLEKMPAMQISR-ISSQNG------ESG----------GGS 653
               |..|.|| |.|         ||......:::.: :|..||      |||          .|.
plant   595 ---LDARAVE-TIL---------PLDASCEDIEVDKDLSFLNGYIQQAIESGAQPYISERERSGM 646

  Fly   654 FDDN-------------------------------SPDVIENGVEGGGGGGHSLIESNMNTLGDN 687
            |:..                               |.:::...........|..|.:::.:..::
plant   647 FETTDYHPQDHHEVPTHALRFEAYELPKPSVPPQASNELVPVPEPSYYSESHQPISTSLVSERES 711

  Fly   688 TNILLDLLG------------------STDLSAGGAGDLVAATDLSNAVHKKNSRNANDVVAPVS 734
            :.|.|.|.|                  :|..:|.|     .:|.....|...:|:       |.|
plant   712 SEIKLRLDGVKQKWGRPSYQSTTAASSTTPQAANG-----ISTHSDAGVGSSSSK-------PRS 764

  Fly   735 NNQDLLDLLDLD--------LSAPSSTTTGAPAGGG-----GGGGIVALVGDNNQSSAANMNNML 786
            :.:.....:|.:        ....||.|....:.||     |.....|.|...||:......::|
plant   765 SYEPKKPEIDPEKQRLAASLFGGSSSRTDKRSSSGGHKPAKGTANKTATVPKENQTPVQPPPDLL 829

  Fly   787 GGLDLGGFGSGLDSSASIPTNGNDLASMLGGLGAPPAASPSL---AASAPVGNLIDGHAGSLLAD 848
                  .||....::|:......:|..::........:|..:   :.:|||.....  ..|||::
plant   830 ------DFGEPTATTATAMDPFKELEGLMDSSSQDGGSSDVMGLYSDAAPVTTTTS--VDSLLSE 886

  Fly   849 LNPTAASNNVVVPPQ---GPRL-TALDKDGLLVQL 879
            |:.::..|:....||   ||.. .||:||.|:.|:
plant   887 LSDSSKGNSRTYQPQTSKGPNTKEALEKDALVRQM 921

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AP-1gamma	NP_788891.2	Adaptin_N	68..624	CDD:279882	150/584 (26%)
AP-1gamma	NP_788891.2	Alpha_adaptinC2	869..972	CDD:197886	6/11 (55%)
AT1G31730	NP_174454.2	Adaptin_N	41..593	CDD:279882	144/562 (26%)
		HEAT repeat	123..148	CDD:293787	9/24 (38%)
		HEAT repeat	157..185	CDD:293787	7/27 (26%)
		HEAT repeat	194..221	CDD:293787	6/28 (21%)
		HEAT repeat	320..351	CDD:293787	7/30 (23%)
		HEAT repeat	363..391	CDD:293787	9/27 (33%)
		HEAT repeat	401..428	CDD:293787	4/26 (15%)
		HEAT repeat	439..461	CDD:293787	5/21 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4354
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250202at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820