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Protein Alignment AP-1gamma and Ap2a2

DIOPT Version :9

Sequence 1:	NP_788891.2	Gene:	AP-1gamma / 31842	FlyBaseID:	FBgn0030089	Length:	982	Species:	Drosophila melanogaster
Sequence 2:	NP_112270.2	Gene:	Ap2a2 / 81637	RGDID:	71015	Length:	939	Species:	Rattus norvegicus

Alignment Length:	977	Identity:	233/977 - (23%)
Similarity:	403/977 - (41%)	Gaps:	220/977 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 MPTPTR---LRDL---IRQIRAARTAAEERAVVNKECAYIRSTFREE---DSVWRCRNIAKLLYI 97
            ||..::   :|.|   |..||..::...|...:|||.|.|||.|:.:   |...:.:.:.|||:|
  Rat     1 MPAVSKGEGMRGLAVFISDIRNCKSKEAEIKRINKELANIRSKFKGDKALDGYSKKKYVCKLLFI 65

  Fly    98 HMLGYPAHFGQLECLKLTASTRFTDKRIGYLGAMLLLDERQDVHLLITNCLKNDLNSSTQFVVGL 162
            .:||:...||.:|.:.|.:|.|:|:|:||||...:|::...::..||.|.:||||.|.....:||
  Rat    66 FLLGHDIDFGHMEAVNLLSSNRYTEKQIGYLFISVLVNSNSELIRLINNAIKNDLASRNPTFMGL 130

  Fly   163 ALCTLGAIASPEMARDLASEVERLMKSPNTY--IRKKATLCAFRVIRRVPELMEI--FLPATRSL 223
            ||..:..:.|.|||...|.|:.:::.:.:|.  :::.|.||..|:.|..|:|:.:  :......|
  Rat   131 ALHCIANVGSREMAEAFAGEIPKILVAGDTMDSVKQSAALCLLRLYRTSPDLVPMGDWTSRVVHL 195

  Fly   224 LSEKNHGILITGVTLITEMCENSSDTLMHFKKDSGNREIVPNLVRILKNLILGGYSPEHDVS--G 286
            |::::.|::....:|||.:.:.:.:   .||..      |...|..|..::....:...|.:  .
  Rat   196 LNDQHLGVVTAATSLITTLAQKNPE---EFKTS------VSLAVSRLSRIVTSASTDLQDYTYYF 251

  Fly   287 VSDPFLQVKILRLLRILGHNDPDA-----SEAMNDILAQVATNTETSK----NVGNTILYETVLS 342
            |..|:|.||:||||:.....:..|     :|.:..||.:.....::.|    |..|.:|:|.:..
  Rat   252 VPAPWLSVKLLRLLQCYPPPEDPAVRGRLTECLETILNKAQEPPKSKKVQHSNAKNAVLFEAISL 316

  Fly   343 IMDIRSEGGLRVLAVNILGRFLLNSDKNIRYVALNTLLRTVHADTS--AVQRHRTTILECLK-DP 404
            |:...||..|.|.|.|.||:||.:.:.|:||:||.::.....::.|  ||:.|..|::..|| :.
  Rat   317 IIHHDSEPNLLVRACNQLGQFLQHRETNLRYLALESMCTLASSEFSHEAVKTHIETVINALKTER 381

  Fly   405 DVSIRRRAMELSFALINAQNIRTMTKELLLFLEKADAEFKAQCSSGMILAAERYSPTTRWHLDTQ 469
            |||:|:||::|.:|:.:..|.:.:..|:|.:||.||...:.:....:.:.||:|:....|::||.
  Rat   382 DVSVRQRAVDLLYAMCDRSNAQQIVAEMLSYLETADYSIREEIVLKVAILAEKYAVDYTWYVDTI 446

  Fly   470 LSVLIAAGNYVRDDVVSSTIQLVSSSPVPEQTYITNRFWESLQVANHCEDKQPLLQVAVWAIGEY 534
            |:::..||:||.::|....||:|.:.. ..|.|.....:|:|| |..|.:.  |::|..:.:||:
  Rat   447 LNLIRIAGDYVSEEVWYRVIQIVINRD-DVQGYAAKTVFEALQ-APACHEN--LVKVGGYILGEF 507

  Fly   535 GD----------LFMYGANEDEFER---PTESDLIAVYYKFLTSAQVSTTSKQYALVSLAKLSTR 586
            |:          |..:.....:|..   ||.:.|::.|.||:........:.|..|.|.::|
  Rat   508 GNLIAGDPRSSPLIQFNLLHSKFHLCSVPTRALLLSTYIKFVNLFPEVKATIQDVLRSDSQL--- 569

  Fly   587 LQQCVEEIQALITSFGSHLNVDLQQRGVEF--------TQLFGHYKHLRPPLLEKMPAMQISRIS 643
                            .:.:|:||||.||:        |.:........||..|:..:: ::::.
  Rat   570 ----------------KNADVELQQRAVEYLRLSTVASTDILATVLEEMPPFPERESSI-LAKLK 617

  Fly   644 SQNGESGGGSFDDNSPDVIENGVEGGGGGGHSLIESNMNTLGDNTNILLDLLGSTDLSAGGAGDL 708
            .:.|.|
  Rat   618 KKKGPS----------------------------------------------------------- 623

  Fly   709 VAATDLSNAVHKKNSRNANDVVAPVSNNQDLLDLLDLDLSAPSSTTTGAPAGGGGGGGIVALVGD 773
             ..|||.. ..::.|.:.|....||                |:||
  Rat   624 -TVTDLEE-TKRERSIDVNGGPEPV----------------PAST-------------------- 650

  Fly   774 NNQSSAANMNNMLGGLDLGGFGSGLDSSASIPTNGNDLASMLGGLGAPPAASPSLAASAPVGNLI 838
                                      |:||.|:...||.    ||||.|.|......::..|.|:
  Rat   651 --------------------------SAASTPSPSADLL----GLGAVPPAPTGPPPTSGGGLLV 685

  Fly   839 D--GHAGSLLADLNPTAASN--NVVVPPQGPRLTALDKDGLLVQLVSVRGSDCMRIYMTTTNNSD 899
            |  ..:.|.:|.|.|.:..|  ..|....|   ...:...|.:.|.|....:..|:::...|.:.
  Rat   686 DVFSDSASAVAPLAPGSEDNFARFVCKNNG---VLFENQLLQIGLKSEFRQNLGRMFIFYGNKTS 747

  Fly   900 ----NTLDQYLLQAAVQRSFQLQMLTPSGSVLPPGGVITQEMRVVATSNATLRMRLRIQYVLDGQ 960
                |.....:....:|.:..|| ..|....:..|..:.|.:.:...|:.|....|.||:...|.
  Rat   748 TQFLNFTPTLICADDLQTNLNLQ-TKPVDPTVDGGAQVQQVVNIECISDFTEAPVLNIQFRYGGT 811

  Fly   961 QQ 962
            .|
  Rat   812 FQ 813

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.