Protein Alignment AP-1gamma and Ap1g2

DIOPT Version :9

• Sequence 1: NP_788891.2
• Gene: AP-1gamma / 31842
• FlyBaseID: FBgn0030089
• Length: 982
• Species: Drosophila melanogaster
• Sequence 2: NP_031481.2
• Gene: Ap1g2 / 11766
• MGIID: 1328307
• Length: 791
• Species: Mus musculus
• Alignment Length: 937
• Identity: 411/937 - (43%)
• Similarity: 538/937 - (57%)
• Gaps: 168/937 - (17%)

  Fly    47 RLRDLIRQIRAARTAAEERAVVNKECAYIRSTFREEDSVWRCRNIAKLLYIHMLGYPAHFGQLEC 111
            ||:|||.:||.|:|.|:||.|:.||||.||::||:.|.:.|.|.:|||||:|||||||||||:||
Mouse     7 RLQDLIEEIRGAKTQAQEREVIQKECAQIRASFRDGDPLQRHRQLAKLLYVHMLGYPAHFGQMEC 71

  Fly   112 LKLTASTRFTDKRIGYLGAMLLLDERQDVHLLITNCLKNDLNSSTQFVVGLALCTLGAIASPEMA 176
            |||.||.||||||:||||||||||||.|.||||||.:||||:...|.|.|||||||..:.|.||.
Mouse    72 LKLIASPRFTDKRVGYLGAMLLLDERHDSHLLITNSIKNDLSQGNQPVQGLALCTLSTMGSAEMC 136

  Fly   177 RDLASEVERLMKSPNTYIRKKATLCAFRVIRRVPELMEIFLPATRSLLSEKNHGILITGVTLITE 241
            ||||.|||:|:..|:.|:||||.|.|..:||:.|||..||||....||.|::|||.:..||||||
Mouse   137 RDLAPEVEKLLLQPSPYVRKKAILTAVHMIRKDPELSGIFLPPCTKLLRERHHGIQLGTVTLITE 201

  Fly   242 MCENSSDTLMHFKKDSGNREIVPNLVRILKNLILGGYSPEHDVSGVSDPFLQVKILRLLRILGHN 306
            :||.:...|.||:|      :||.||:||:.|:..|||.||.:||||||||||:|||||||||.|
Mouse   202 LCERNPAALRHFRK------VVPQLVQILRTLVTTGYSTEHSISGVSDPFLQVQILRLLRILGRN 260

  Fly   307 DPDASEAMNDILAQVATNTETSKNVGNTILYETVLSIMDIRSEGGLRVLAVNILGRFLLNSDKNI 371
            ..::||.|||:||||||||:||:|.||.:|.||||:||.|.|..||||||||||||||||:||||
Mouse   261 HEESSETMNDLLAQVATNTDTSRNAGNAVLLETVLTIMAIHSAAGLRVLAVNILGRFLLNNDKNI 325

  Fly   372 RYVALNTLLRTVHADTSAVQRHRTTILECLKDPDVSIRRRAMELSFALINAQNIRTMTKELLLFL 436
            |||||.:||:.|.:|.|||||||:|::|||::.|.|:.|||:|||.||:|:.|:|.|.:||..||
Mouse   326 RYVALTSLLQLVQSDHSAVQRHRSTVVECLQETDASLSRRALELSLALVNSSNVRAMMQELQAFL 390

  Fly   437 EKADAEFKAQCSSGMILAAERYSPTTRWHLDTQLSVLIAAGNYVRDDVVSSTIQLVSSSPVPEQ- 500
            |....:.:|.|:||::|||||::|:.|||:||.|.||..||.:||||.|::..||:..:   |:
Mouse   391 ESCPPDLRADCASGILLAAERFAPSKRWHIDTILHVLTTAGAHVRDDAVANLTQLIGEA---EEL 452

  Fly   501 -TYITNRFWESLQVANHCED--KQPLLQVAVWAIGEYGDLFMYG-ANEDEFERPTESDLIAVYYK 561
             ||...|.:.:|     .||  :|||:|||.|.|||||||.:.| ..|.|..:..|.|::|:..|
Mouse   453 HTYSVRRLYSAL-----AEDISQQPLVQVAAWCIGEYGDLLLEGNCEETEPFQVEEEDVLALLEK 512

  Fly   562 FLTSAQVSTTSKQYALVSLAKLSTRLQQCVEEIQALITSFGSHLNVDLQQRGVEFTQLFGHYKHL 626
            .|.|......::.||:.:|.||||||:.....|:.:::.:||.::::||||.||:..||..|.|:
Mouse   513 VLQSHMSLPATRGYAITALMKLSTRLRGDNNRIRQVVSIYGSCVDLELQQRAVEYNTLFQKYDHM 577

  Fly   627 RPPLLEKMPAMQISRISSQNGESGGGSFDDNSPDVIENGVEGGGGGGHSLIESNMNTLGDNTNI- 690
            |..:|||||.:          |.|       .|.|.|.|.|.........:.:...|....|.:
Mouse   578 RAAILEKMPLV----------ERG-------DPHVKEGGKEKQTEAQPLEVTAPAPTEPQATKLL 625

  Fly   691 -LLDLLGSTD--LSAGGAGDLVAATDLSNAVHKKNSRNANDVVAPVSNNQDLLDLLDLDLSAPSS 752
             ||||||.|.  ||:|.|..|...|.                    |..:.|:.||||..:.|
Mouse   626 DLLDLLGDTSEPLSSGHAQHLPPQTP--------------------SPGEALIHLLDLPCTPP-- 668

  Fly   753 TTTGAPAGGGGGGGIVALVGDNNQSSAANMNNMLGGLDLGGFGSGLDSSASIPTNGNDLASMLGG 817
                                                                             
Mouse   669 ----------------------------------------------------------------- 668

  Fly   818 LGAPPAASPSLAASAPVGNLIDGHAGSLLADLNPTAASNNVVVPPQGPRLTALDKDGLLVQLVSV 882
               |||..||:......|..:|      |:.:.|                  |:...||:
Mouse   669 ---PPAPIPSVRVFEREGLQLD------LSFMRP------------------LETPALLL----- 701

  Fly   883 RGSDCMRIYMTTTNNSDNTLDQYLLQAAVQRSFQLQMLTPSGSVLP-PGGV-ITQEMRVVATSNA 945
                   :..||||:|...:..::.||||.:|||||:..|||:.:| .||: |||..|::..:.|
Mouse   702 -------VTATTTNSSKEDVTHFVCQAAVPKSFQLQLQAPSGNTIPAQGGLPITQVFRILNPNQA 759

  Fly   946 TLRMRLRIQYVLDGQQQVEQTEVSGFP 972
            .||::||:.|...||...|..||...|
Mouse   760 PLRLKLRLTYNHSGQPVQEIFEVDNLP 786

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AP-1gamma	NP_788891.2	Adaptin_N	68..624	CDD:279882	313/560 (56%)
		Alpha_adaptinC2	869..972	CDD:197886	38/104 (37%)
Ap1g2	NP_031481.2	Adaptin_N	24..575	CDD:279882	316/564 (56%)
		Alpha_adaptinC2	678..786	CDD:197886	42/143 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167845815
Domainoid	1	1.000	713	1.000	Domainoid score	I116
eggNOG	1	0.900	-	-		E1_COG4354
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	769	1.000	Inparanoid score	I538
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53727
OrthoDB	1	1.010	-	-		D250202at2759
OrthoFinder	1	1.000	-	-		FOG0002071
OrthoInspector	1	1.000	-	-		otm42734
orthoMCL	1	0.900	-	-		OOG6_101228
Panther	1	1.100	-	-	O	PTHR22780
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2030
SonicParanoid	1	1.000	-	-		X1368
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.800