DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Arfrp1 and ARL13B

DIOPT Version :9

Sequence 1:	NP_572526.1	Gene:	Arfrp1 / 31841	FlyBaseID:	FBgn0030088	Length:	200	Species:	Drosophila melanogaster
Sequence 2:	NP_001167621.1	Gene:	ARL13B / 200894	HGNCID:	25419	Length:	428	Species:	Homo sapiens

Alignment Length:	201	Identity:	66/201 - (32%)
Similarity:	104/201 - (51%)	Gaps:	21/201 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MYTLMHG----FYKYMTQKDDYCVVILGLDNAGKTTYLEAAKTTFTRNYKGLNPSKITTTVGLNI 61
            |::||..    |.::........::::||||||        ||...:..:|..|..:..|||.:.
Human     1 MFSLMASCCGWFKRWREPVRKVTLLMVGLDNAG--------KTATAKGIQGEYPEDVAPTVGFSK 57

  Fly    62 GTIDVQGVRLNFWDLGGQQELQSLWDKYYQESHGVIYVIDSNDRERMEESKAIFDKMIKNELLSG 126
            ..:......:..:||||...::.:|..||.||:|||:|:||:|.|||||:|....:|:::..:||
Human    58 INLRQGKFEVTIFDLGGGIRIRGIWKNYYAESYGVIFVVDSSDEERMEETKEAMSEMLRHPRISG 122

  Fly   127 VPLLILANKQDLPDVMGVREIKPVFQQAGALIGRRDCL--TIPVSALHGEG--VDEGIK----WL 183
            .|:|:||||||....:|..::.... ....|:....||  ..|.||:.|.|  :|:.||    ||
Human   123 KPILVLANKQDKEGALGEADVIECL-SLEKLVNEHKCLCQIEPCSAISGYGKKIDKSIKKGLYWL 186

  Fly   184 VEAIKR 189
            :..|.|
Human   187 LHVIAR 192

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Arfrp1	NP_572526.1	small_GTP	17..181	CDD:272973	56/167 (34%)
Arfrp1	NP_572526.1	Arfrp1	19..186	CDD:206725	60/174 (34%)
ARL13B	NP_001167621.1	Arl2l1_Arl13_like	23..189	CDD:133361	60/174 (34%)
		RNase_E_G	<198..>259	CDD:331378
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	207..287
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	318..428
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0076
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810