Protein Alignment Bx42 and prp45

DIOPT Version :9

• Sequence 1: NP_001259370.1
• Gene: Bx42 / 31840
• FlyBaseID: FBgn0004856
• Length: 547
• Species: Drosophila melanogaster
• Sequence 2: NP_588213.1
• Gene: prp45 / 2538988
• PomBaseID: SPCC188.11
• Length: 557
• Species: Schizosaccharomyces pombe
• Alignment Length: 562
• Identity: 254/562 - (45%)
• Similarity: 347/562 - (61%)
• Gaps: 64/562 - (11%)

  Fly     3 LSSLLPTPTNAIWDREDERRLVARGAPKIGALVSAKIAAPPYGQRKDWVPHTDADFGDGGAFPEI 67
            |||:||.|.   :|.|:|..:....:......:..|...|||||||.|.|.:..|||||||||||
pombe     8 LSSILPNPD---FDDEEEDYVERETSHADERQIGVKFHIPPYGQRKGWFPSSPEDFGDGGAFPEI 69

  Fly    68 HVAQYPLGLGAPGNVGKKSDALAVRLDDKGKVKYDAIARQGHGKDKIVYSSISQLLPAEV-LAED 131
            |||||||.:|...:.....:.||:::...|.|.|:|||||||...::|.:|...|:|... |...
pombe    70 HVAQYPLDMGRKRSAKSAGNTLALQVTSSGAVDYNAIARQGHEHGELVQASFRDLIPLRARLGVG 134

  Fly   132 ADELQRPDEETVMETTEETRLALEKLTNQKITSALPVRHA--QKAGPAQYIRYTPS-QQGDTFNS 193
            ...|::|.:|...|...:|:|||:|:.:::|..:.|....  |:..|. ||||||| |.|...
pombe   135 EISLEKPSDEQKQEVANKTKLALQKILSKQIAQSQPKSAVVQQRDDPV-YIRYTPSNQMGQAL-- 196

  Fly   194 GAKQRVIRMVEAQLDPMEPPKFRINKKIPRGPPSPPAPVLHSPSRKVTVKEQKEWKIPPCISNWK 258
             :|||:|:||.|:.||||||||| :||:||||||||.||||||.|||:.:||::|:|||.|||||
pombe   197 -SKQRIIKMVTAEQDPMEPPKFR-HKKVPRGPPSPPPPVLHSPPRKVSAQEQQDWQIPPSISNWK 259

  Fly   259 NAKGYTIPLDKRLAADGRGLQQVHINEKFAKMAEALYIADRKAREAVEARSQLEKKLAQKEKEKK 323
            |.||||||||||||||||||..|.||:.|||.:||||..:|:|||.|..|:.:.:|:|:|||::|
pombe   260 NPKGYTIPLDKRLAADGRGLNDVEINDGFAKFSEALYTVERQAREEVRYRAIMRQKMAEKEKQEK 324

  Fly   324 EDMLRMMAQRAREERAGLRN-----PEAAEPSGSGATGSE------------------------V 359
            |..|.|:||:|||:|.| ||     |..|:|..:..:..|                        .
pombe   325 EQRLFMLAQKAREDRMG-RNAASSGPSHAKPRSTSVSSEERSRSRAGSFSHHSESENEDEDSEAF 388

  Fly   360 RERNDLRAERQRERQRDRNLQRAAPEKRSKL-QKERERDISEQIALGLPAKSAGNGETLFDQRLF 423
            |.|.:||.||:|:.::|..|.|...|||:|| :|:|.||::|::|||| :|.:.:.:|:.|.|||
pombe   389 RRRQELRRERRRQAEKDLRLSRMGAEKRAKLAEKDRPRDVAERVALGL-SKPSMSSDTMIDSRLF 452

  Fly   424 NTTKGMDSGYGDDEAYNVYDKPWR--DSNTLGAHIYRP----SKQADSDNYGGDLDAIVNTKRF- 481
            |...|:.||:.|:::|||||||||  .|:||    |||    |:|.|:   ..:|:.|.:..|:
pombe   453 NQASGLGSGFQDEDSYNVYDKPWRAAPSSTL----YRPGATLSRQVDA---SAELERITSESRYD 510

  Fly   482 ---VPDKQFSGASKEAAAGQRSGPVEFEKE-EDPFGLDQFLN 519
               ...|:|.|:  :.....|:|||.|||: .||||:|.|||
pombe   511 VLGNAHKKFKGS--DEVVESRAGPVTFEKDIADPFGVDTFLN 550

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Bx42	NP_001259370.1	SKIP_SNW	181..337	CDD:280827	101/156 (65%)
prp45	NP_588213.1	SKIP_SNW	185..338	CDD:280827	101/156 (65%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	213	1.000	Domainoid score	I590
eggNOG	1	0.900	-	-		E1_KOG2441
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H56557
Inparanoid	1	1.050	433	1.000	Inparanoid score	I320
OMA	1	1.010	-	-		QHG55207
OrthoFinder	1	1.000	-	-		FOG0005122
OrthoInspector	1	1.000	-	-		oto101216
orthoMCL	1	0.900	-	-		OOG6_102543
Panther	1	1.100	-	-	LDO	PTHR12096
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R994
SonicParanoid	1	1.000	-	-		X3642
TreeFam	1	0.960	-	-
	14	13.860