DRSC/TRiP Functional Genomics Resources

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Protein Alignment HNRNPD and HRP1

DIOPT Version :9

Sequence 1:NP_112738.1 Gene:HNRNPD / 3184 HGNCID:5036 Length:355 Species:Homo sapiens
Sequence 2:NP_014518.1 Gene:HRP1 / 853997 SGDID:S000005483 Length:534 Species:Saccharomyces cerevisiae


Alignment Length:350 Identity:113/350 - (32%)
Similarity:168/350 - (48%) Gaps:59/350 - (16%)


- Green bases have known domain annotations that are detailed below.


Human    21 GSAGEQEGA---------MVAATQGAAAAAGSGAGTGG-------GTASGGTEGGSAESEGAKID 69
            |:|.::||:         ..:||...|.|..|.||..|       .|.|...:..|......::.
Yeast    79 GTANDKEGSNEDTKNEKKQESATSANANANASSAGPSGLPWEQLQQTMSQFQQPSSQSPPQQQVT 143

Human    70 ASKNEEDEGHSNSSPRHSEAATAQREEWKMFIGGLSWDTTKKDLKDYFSKFGEVVDCTLKLDPIT 134
            .:|.|..:            |...:|..|||||||:||||:.:|::||.|:|.|.|..:..||.|
Yeast   144 QTKEERSK------------ADLSKESCKMFIGGLNWDTTEDNLREYFGKYGTVTDLKIMKDPAT 196

Human   135 GRSRGFGFVLFKESESVDKVMDQKEHKLNGKVIDPKRAKAMKTKEPVKKIFVGGLSPDTPEEKIR 199
            ||||||||:.|::..|||:|: :.:|.|:|||||||||.....::...||||||:.||...::..
Yeast   197 GRSRGFGFLSFEKPSSVDEVV-KTQHILDGKVIDPKRAIPRDEQDKTGKIFVGGIGPDVRPKEFE 260

Human   200 EYFGGFGEVESIELPMDNKTNKRRGFCFITFKEEEPVKKIMEKKYHNVGLSKCEIKVAMSKEQYQ 264
            |:|..:|.:...:|.:|..|.:.|||.|:|:...:.|.::.:.|:.:....|.|||    :.:.:
Yeast   261 EFFSQWGTIIDAQLMLDKDTGQSRGFGFVTYDSADAVDRVCQNKFIDFKDRKIEIK----RAEPR 321

Human   265 QQQQWGSRGGFAGRARGRGGGPSQNWNQGYSNYWNQGYGNYGYNSQGYGGYGGY-------DYTG 322
            ..||..|..|      |..||  .|.|:...|:.|||..|..|.:...|||...       ||  
Yeast   322 HMQQKSSNNG------GNNGG--NNMNRRGGNFGNQGDFNQMYQNPMMGGYNPMMNPQAMTDY-- 376

Human   323 YNNYYGYGDYSNQQSGYGKVSRRGG 347
                     |...|..|.::.::.|
Yeast   377 ---------YQKMQEYYQQMQKQTG 392

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
HNRNPDNP_112738.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..92 18/86 (21%)
CBFNT <60..78 CDD:311868 3/17 (18%)
RRM1_hnRNPD 99..172 CDD:410150 42/72 (58%)
RRM2_hnRNPD 183..257 CDD:241027 25/73 (34%)
HRP1NP_014518.1 PABP-1234 <144..463 CDD:130689 97/284 (34%)
RRM1_Hrp1p 161..236 CDD:409991 44/75 (59%)
RRM2_Hrp1p 244..321 CDD:409767 25/80 (31%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 1 1.000 77 1.000 Domainoid score I2313
eggNOG 00.000 Not matched by this tool.
Hieranoid 1 1.000 - -
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 169 1.000 Inparanoid score I1143
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
43.960

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