Protein Alignment HNRNPD and sqd

DIOPT Version :10

• Sequence 1: NP_112738.1
• Gene: HNRNPD / 3184
• HGNCID: 5036
• Length: 355
• Species: Homo sapiens
• Sequence 2: NP_731825.1
• Gene: sqd / 41666
• FlyBaseID: FBgn0263396
• Length: 344
• Species: Drosophila melanogaster
• Alignment Length: 306
• Identity: 124/306 - (40%)
• Similarity: 177/306 - (57%)
• Gaps: 31/306 - (10%)

Human    51 TASG-GTEGGSAESEGAKIDASKNEEDEGHSNSSPRHSEAATAQR-EEWKMFIGGLSWDTTKKDL 113
            ||.| |:|.|.|.:.|:             :|.|..:..||:.|| ::.|:|:|||||:||:|:|
  Fly    21 TADGPGSENGDAGAAGS-------------TNGSSDNQSAASGQRDDDRKLFVGGLSWETTEKEL 72

Human   114 KDYFSKFGEVVDCTLKLDPITGRSRGFGFVLFKESESVDKVMDQKEHKLNGKVIDPKRAKAMKTK 178
            :|:|.|:||:....:|.||.|||||||.|::|..:|::|||....||.:|.|.:|||:|||..
  Fly    73 RDHFGKYGEIESINVKTDPQTGRSRGFAFIVFTNTEAIDKVSAADEHIINSKKVDPKKAKARH-- 135

Human   179 EPVKKIFVGGLSPDTPEEKIREYFGGFGEVESIELPMDNKTNKRRGFCFITFKEEEPVKKIMEKK 243
               .|||||||:.:..:|:|:.|||.||.:..:|:|.|.:.::|:|||||||..|:.|..:::..
  Fly   136 ---GKIFVGGLTTEISDEEIKTYFGQFGNIVEVEMPFDKQKSQRKGFCFITFDSEQVVTDLLKTP 197

Human   244 YHNVGLSKCEIKVAMSKEQYQQQQQWGSRGGFAGRARGRGGGPSQNWNQGYSNYWNQGYGNYGYN 308
            ...:...:.::|.|..|.  :.|...|.|||..|..||..||  .....||:|.|: |.|:||
  Fly   198 KQKIAGKEVDVKRATPKP--ENQMMGGMRGGPRGGMRGGRGG--YGGRGGYNNQWD-GQGSYG-- 255

Human   309 SQGY-GGYGGYDYTGYNNYYGYGDYSNQQSGYGKVSRRGGHQ-NSY 352
              || ||||||...||.:||..|.|:....||......||.: |.|
  Fly   256 --GYGGGYGGYGAGGYGDYYAGGYYNGYDYGYDGYGYGGGFEGNGY 299

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HNRNPD	NP_112738.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..92		12/41 (29%)
		CBFNT	<60..78	CDD:311868	2/17 (12%)
		RRM1_hnRNPD	99..172	CDD:410150	38/72 (53%)
		RRM2_hnRNPD	183..257	CDD:241027	28/73 (38%)
sqd	NP_731825.1	RRM1_hnRNPA_hnRNPD_like	58..129	CDD:409763	36/70 (51%)
		RRM2_hnRNPD_like	137..211	CDD:240775	28/73 (38%)