DRSC/TRiP Functional Genomics Resources

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Protein Alignment HNRNPD and CG4612

DIOPT Version :9

Sequence 1:NP_112738.1 Gene:HNRNPD / 3184 HGNCID:5036 Length:355 Species:Homo sapiens
Sequence 2:NP_001246493.1 Gene:CG4612 / 37914 FlyBaseID:FBgn0035016 Length:307 Species:Drosophila melanogaster


Alignment Length:300 Identity:77/300 - (25%)
Similarity:129/300 - (43%) Gaps:67/300 - (22%)


- Green bases have known domain annotations that are detailed below.


Human     3 EEQFGGDGAAAAATAAVGGSAGEQEGAMVAATQG--------------AAAAAGSGAGTGGGTAS 53
            ::|.....|||...:.|||..........||..|              ::.:|..|.|.|||..:
  Fly    33 QQQLHHHAAAAGHLSHVGGGHAASNHLAAAAVLGRHGHNSLGSGHTSTSSHSANVGVGVGGGALA 97

Human    54 GGTEGGSAESEGAKIDASKNEEDEGHSNSSPRHSEAATAQREEWKMFIGGLSWDTTKKDLKDYFS 118
            .|:.|||.                  .||||          :..|::|..|......|.:.|.||
  Fly    98 SGSTGGSG------------------GNSSP----------DSGKIYIKNLERSIDNKAVYDTFS 134

Human   119 KFGEVVDCTLKLDPITGRSRGFGFVLFKESE----SVDKV-----MDQKEHKLNGKVIDPKRAKA 174
            .||.:::|.:..|. .|.|||:|||.|...|    :::||     .:||.|.:  |.| |:|.:.
  Fly   135 VFGNILNCNVAKDE-DGNSRGYGFVHFDSEEAARAAIEKVNGMLCNNQKVHVV--KFI-PRRDRE 195

Human   175 MKTKEPVKKIFVGGLSPDTPEEKIREYFGGFGEVESIELPMDNKTNKRRGFCFITFKEEEPV--- 236
            .:.....|.::|..||.:..|:.:||.|..:|.:.|.:|.:|.:...|| |.|:.::..:..   
  Fly   196 QEKATHFKNLYVKNLSEEFTEQHLREMFEPYGRITSHKLMLDEEGRSRR-FGFVAYENPQSALAA 259

Human   237 ------KKIMEKKYHNV--GLSKCEIKVAMSKEQYQQQQQ 268
                  |::.:.|:..|  .|||.|.:..::::..::::|
  Fly   260 VIGLHGKQLGDNKFLYVARALSKAERQQEINRKLEERKRQ 299

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
HNRNPDNP_112738.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..92 24/102 (24%)
CBFNT <60..78 CDD:311868 1/17 (6%)
RRM1_hnRNPD 99..172 CDD:410150 27/81 (33%)
RRM2_hnRNPD 183..257 CDD:241027 22/84 (26%)
CG4612NP_001246493.1 RRM2_I_PABPs 115..185 CDD:240825 23/70 (33%)
RRM3_I_PABPs 202..282 CDD:240826 20/80 (25%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 1 0.960 - -
User_Submission 00.000 Not matched by this tool.
21.870

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