Protein Alignment CG7766 and phka1a

DIOPT Version :10

• Sequence 1: NP_001245588.1
• Gene: CG7766 / 31839
• FlyBaseID: FBgn0030087
• Length: 1358
• Species: Drosophila melanogaster
• Sequence 2: XP_005166576.1
• Gene: phka1a / 572183
• ZFINID: ZDB-GENE-031118-56
• Length: 1232
• Species: Danio rerio
• Alignment Length: 1430
• Identity: 621/1430 - (43%)
• Similarity: 826/1430 - (57%)
• Gaps: 302/1430 - (21%)

  Fly     1 MRSRSNSGVRLDYYQRIVHRLILAHQEPVTGLFPASNVNSHAWIRDNVYCILAVWGLSMAYKKIA 65
            |||||||||:||.|.||||:.||.||:|||||.|||.....||:|||||.||:||.||:||:|.|
Zfish     1 MRSRSNSGVKLDNYARIVHQTILRHQDPVTGLLPASKEQPDAWVRDNVYSILSVWALSLAYRKNA 65

  Fly    66 DQDEDRAKCYELEQSCVKLMRGLLMAMMNQKDKVEKFKMTQSPYDSLHAKYSSKNGLPVVDDNEW 130
            |:|||:||.||||||.||||||:|..:|.|.|||||||.::|..|||||||:::....||.|.||
Zfish    66 DRDEDKAKAYELEQSVVKLMRGVLQCIMRQLDKVEKFKYSKSALDSLHAKYNTRTCATVVGDREW 130

  Fly   131 GHLQIDAVSLYLLILAQMTASGLQIVFSLDEVSFIQNLVFYIESAYSIPDYGIWERGDKTNHGEP 195
            ||||:||.|||:|.|||||||||.||::.|||..:|||:||||:||.:.|||:||||||||.|.|
Zfish   131 GHLQLDATSLYMLFLAQMTASGLHIVYTQDEVDVVQNLLFYIEAAYKVADYGMWERGDKTNQGIP 195

  Fly   196 ELNASSIGMAKAALEAMNELDLFGARGGPASVIHVLADEAHKCQAVLQSMLPRESNSKELDSGLL 260
            ||||||||||||||||:::|:||||:|||.||:|||||:...||::|.|||||.|.|||:|:|||
Zfish   196 ELNASSIGMAKAALEALDDLNLFGAKGGPDSVVHVLADDIQHCQSILNSMLPRASTSKEVDAGLL 260

  Fly   261 CVIGFPAFAVDDAQLIHNTKDAILSRLQGKYGCKRFLRDGYRTPKEDPSRLYYERWELRMFENIE 325
            .:|.:|||||:|.:|::.||:.|:|:|||:|||.||||||::||||||:|||||..||::|||||
Zfish   261 SIISYPAFAVEDMELVNITKEEIISKLQGRYGCCRFLRDGHKTPKEDPNRLYYESAELKLFENIE 325

  Fly   326 CEWPLFYCYLILFHAFQSDKRAVEEYASRLEKIMVRSEDGILLVPESYAVPQDLVGFEYQKPGSQ 390
            ||||||:.||||...|.:....||||...||.|:::.:|||.|:||.|:||.:.|..||..|.:.
Zfish   326 CEWPLFWTYLILDGIFINSPEQVEEYREALEGILIKQKDGIRLLPELYSVPPEKVDEEYVNPHTV 390

  Fly   391 VREVVGRCPFLWGQSLFILGRLLQEGFLAVGELDPLNRRLGAQKKPDVVVQVVIIAEDNEIRDKL 455
            .|..:|:||..|||||::||.||.|||||.||:||||||..|..||||||||.|:||:.:|:..|
Zfish   391 ERIPLGKCPLKWGQSLYVLGNLLAEGFLAPGEIDPLNRRFSAIPKPDVVVQVSILAENEDIKALL 455

  Fly   456 AEHDLHVQTIAEVAPIEVQPARVLSHLYTYLGRNRKLGLSGRKSRDVGILSTSKLYSLKDRIFAF 520
            .::.:.|:|:|::.||.|||:|||||:|..||||.:|||:||..|.:|:|.|||||.:::.||:|
Zfish   456 QKNGIDVETVADIHPIRVQPSRVLSHIYARLGRNERLGLTGRPYRRIGVLGTSKLYIIRNTIFSF 520

  Fly   521 TPQHIDYEEYYTTRDPDLLASNFTTNLAFLTNNWRHMLGRPTITLMATHYMLDQDKIPL--AMIQ 583
            |||.||::::|...|..::.....|:|::|::.|| |.||||:|...:..||:.|...|  |::.
Zfish   521 TPQFIDHQQFYLALDNKMIVEMLRTDLSYLSSRWR-MTGRPTVTFPISQTMLNHDHTDLDPAVLA 584

  Fly   584 TMRKLKSGYINGTRVMLGSLKDFLNTSAITDLSFLGS--------------TEDGY-PDRLH--- 630
            |::||:.||..|.||..|.|.:||.|.....||||.|              .||.| ...:|
Zfish   585 TLKKLQDGYFGGARVQTGKLSEFLTTCCCAHLSFLDSGKTRSNKGWDEDDDVEDDYFRGAVHDLN 649

  Fly   631 -----PDVQTYLDEHLLRSFSNRSTMNLRGGQLRPRTLRRRMS-CKGAIKKTRS----INVDSD- 684
                 .|:..|||:.|      .:.:.::|  ||.....:.:| .|.|..|||.    :|...|
Zfish   650 FSDDSDDLAQYLDQLL------HAAVPVQG--LRVEAEAKGLSRFKAAATKTREMVSLVNKAKDL 706

  Fly   685 ---NLGMEGPSPLTERRLSSIVPPPWLQANKQSHVSVFATTPEEGPTSSPLSLGNDLIRENIYPV 746
               ||.|..|:.|...      |.|             |...::.|     .||.|...|.:.|.
Zfish   707 QIHNLHMYLPNKLFRS------PQP-------------ALNLKDFP-----GLGTDHSSEVVVPS 747

  Fly   747 D---PHHSRSAIDRRSEFVRQQEITVPKILIQRHRAETNFADTEVEELIAMLRETENLEEQGDIL 808
            :   |..:..|||..|                               |:.:|::|::|.:|.|||
Zfish   748 ENNLPRDTHGAIDYSS-------------------------------LVQVLKDTQSLHDQADIL 781

  Fly   809 QYLVDTQGLDFNTAGLGFKNKSEENATPNANNAELEQAFVDDAVLELADGGGGAGAGAGGGDGAK 873
            ..|              ||:|
Zfish   782 YIL--------------FKDK-------------------------------------------- 788

  Fly   874 KSPTIVLPTVIIDAATIPAGTGTDPDNAAHPSSATANSNNSHCIGNTSNISSSSSNISNHNNMSP 938
                                 |.|.|...|
Zfish   789 ---------------------GMDWDTQLH----------------------------------- 797

  Fly   939 HENNHDSSQSEGMLEEGRVVTVRDLLKGLYEKACQQKLWGLVRHTAGMLGKRVEDLAKAVTDLLV 1003
                            |:..||:.||..|||||...:.|.::|..:|||.|:||:|..|.:|||.
Zfish   798 ----------------GKGTTVKSLLVELYEKAGDLRCWDIIRMISGMLRKKVEELDWACSDLLA 846

  Fly  1004 RQKQVTVGMPPN-NEHTITAPLPEVELRQLIHDAYGDDESTAMLTQELMVYLAMFIRTEPQLFHE 1067
            .||.:|||:||. .|.|||||||..:|..||..|..:..:.|:||||::|||||.|||:..||.|
Zfish   847 HQKHLTVGLPPEPREKTITAPLPPDQLALLIDQASENSITIAILTQEIIVYLAMIIRTQRSLFSE 911

  Fly  1068 MLRLRVGLIIQVMAKELSRTLNCDGEAASEHLLNLSPFEMKNLLYHILSGKEFAVSSVAR----- 1127
            |.|||:||||||||.||:::|||.||.|:|.|:.|||.|:||||:||||||||.|....|
Zfish   912 MFRLRIGLIIQVMATELAQSLNCSGEEATESLMKLSPSELKNLLHHILSGKEFGVQRSVRSVEPG 976

  Fly  1128 ----------GNLSIVSCKSSRVSK-KSQIGL---------------------GDP--------- 1151
                      ||:.....:.:.:|| ||.:.:                     .:|
Zfish   977 VSPVISIHEVGNVGATKSERAGISKLKSDMKMLEELRFSWSIQSKTFSGQSFDAEPVELARSRMP 1041

  Fly  1152 --EGEDALIAT---IDDRQGQWLRRRRLDGALNRVPRDFYSRVWTVLEKCQGLAIEGRVLQQSLT 1211
              :|.|:.::.   .|.|||||||||||||||||||..||.:||.:|:||.||:|||.||..|.|
Zfish  1042 SIDGFDSSVSVGVPRDSRQGQWLRRRRLDGALNRVPVGFYQKVWKILQKCHGLSIEGFVLPSSTT 1106

  Fly  1212 QEMTPGELKFALEVETALNQIPQPEYRQLVVEALMVLTLVTEHNMVPSLGGVIYVEHLVHKANQL 1276
            :||||||:|||:.||..||::||||||||:||.::|||::.:.: :.|:|.:|::|.:||.||.:
Zfish  1107 REMTPGEIKFAVHVERVLNRVPQPEYRQLLVEGILVLTMLADVD-IQSIGSIIHIEKIVHIANDM 1170

  Fly  1277 FLEDQRKVQGDATLCCAKIKDGKEQQQAASGMLLCGGAAYICQHLYDSAPSGSYGTMTYMSRAVA 1341
            |.:||:.:..:.::.        |:.|:..          ||:.|||:||||.:|||||:::|||
Zfish  1171 FYKDQKDLGAEDSIL--------EKDQSTG----------ICRLLYDTAPSGRFGTMTYLTKAVA 1217

  Fly  1342  1341
            Zfish  1218  1217

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7766	NP_001245588.1	Glyco_hydro_15	8..>439	CDD:395586	275/430 (64%)
		Bac_rhamnosid6H	<959..1075	CDD:481215	61/116 (53%)
		KPBB_C	1086..>1260	CDD:437124	97/224 (43%)
phka1a	XP_005166576.1	Glyco_hydro_15	8..>439	CDD:395586	275/430 (64%)
		Bac_rhamnosid6H	<802..919	CDD:481215	61/116 (53%)
		KPBB_C	930..>1143	CDD:437124	94/212 (44%)