Protein Alignment CCT2 and CCT6A

DIOPT Version :10

• Sequence 1: NP_572524.1
• Gene: CCT2 / 31838
• FlyBaseID: FBgn0030086
• Length: 535
• Species: Drosophila melanogaster
• Sequence 2: NP_001753.1
• Gene: CCT6A / 908
• HGNCID: 1620
• Length: 531
• Species: Homo sapiens
• Alignment Length: 536
• Identity: 151/536 - (28%)
• Similarity: 286/536 - (53%)
• Gaps: 37/536 - (6%)

  Fly     8 VRVLKNEAQEEKAEMARLSSFIGAIAIGDLVKSTLGPKGMDKILVATGRNAGHVEVTNDGATILR 72
            |:.|..:|:..:|:.|...:...|..:.|::::.|||||..|:||:   .||.:::|.||..:|.
Human     4 VKTLNPKAEVARAQAALAVNISAARGLQDVLRTNLGPKGTMKMLVS---GAGDIKLTKDGNVLLH 65

  Fly    73 AVGVDNPAAKILVDMSRVQDEEVGDGTTSVTVLASELLREAEKLVEQKLHPQIIVSGWRQATQVA 137
            .:.:.:|.|.::..::..||:..||||||..::..|||::|:..:.:.|||:||..|:..|.:.|
Human    66 EMQIQHPTASLIAKVATAQDDITGDGTTSNVLIIGELLKQADLYISEGLHPRIITEGFEAAKEKA 130

  Fly   138 LEALTAAAQDNSSSDEKFRNDLLNIARTTLSSKILHQHKDFFANLAVDAVMRLKGSGE---LKSI 199
            |:.|    ::...|.|..|..|:::|||:|.:|:..:..|......||:::.:|...|   |..|
Human   131 LQFL----EEVKVSREMDRETLIDVARTSLRTKVHAELADVLTEAVVDSILAIKKQDEPIDLFMI 191

  Fly   200 QIIKKSGGTLGDSFLDEGFLLDKKPGVHQP---QRIENARILIANTPMDTDKIKVFGSSIKVDSL 261
            :|::....:..|:.|..|.:||.  |...|   :|:|:|.||..|..::.:|.:| .|.....|.
Human   192 EIMEMKHKSETDTSLIRGLVLDH--GARHPDMKKRVEDAYILTCNVSLEYEKTEV-NSGFFYKSA 253

  Fly   262 AKIADLEMAEKEKMKEKVDKILKHK---CN------VFINRQLIYNYPEQLFADARVMSIEHADF 317
            .:...|..||::.::::|.||::.|   |.      |.||::.|..:.....:...::::..|..
Human   254 EEREKLVKAERKFIEDRVKKIIELKRKVCGDSDKGFVVINQKGIDPFSLDALSKEGIVALRRAKR 318

  Fly   318 DGIERLAYCTGGEIVSTFENPSLVKLGECDVIEQVMIGEDTLLRFSGVKLGEAC------TIVIR 376
            ..:|||....||..:::|::.|...||...::.:..:||:   :|:.:   |.|      |::|:
Human   319 RNMERLTLACGGVALNSFDDLSPDCLGHAGLVYEYTLGEE---KFTFI---EKCNNPRSVTLLIK 377

  Fly   377 GATQQILDEADRSLHDALCVLAATVKESRIIFGGGCSEALMATAVLKKAAETPGKEAIAIEAFAR 441
            |..:..|.:...::.|.|..:...:.:..::.|.|..|..||.|::|......|:..:.::|||.
Human   378 GPNKHTLTQIKDAVRDGLRAVKNAIDDGCVVPGAGAVEVAMAEALIKHKPSVKGRAQLGVQAFAD 442

  Fly   442 ALLSLPTAIADNAGYDSAQLVSELRAGHAQGKQTLGLDMELGKVADVRELGITESFAVKRQVLMS 506
            |||.:|..:|.|:|:|..:.:.:::|.|::..|.:|:|:..|:.....|:|:.:::.||:|:|.|
Human   443 ALLIIPKVLAQNSGFDLQETLVKIQAEHSESGQLVGVDLNTGEPMVAAEVGVWDNYCVKKQLLHS 507

  Fly   507 ASEAAEMILRVDNIIR 522
            .:..|..||.||.|:|
Human   508 CTVIATNILLVDEIMR 523

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCT2	NP_572524.1	TCP1_beta	10..527	CDD:239452	150/534 (28%)
CCT6A	NP_001753.1	chap_CCT_zeta	3..530	CDD:274088	151/536 (28%)