Protein Alignment CCT2 and CCT3

DIOPT Version :10

• Sequence 1: NP_572524.1
• Gene: CCT2 / 31838
• FlyBaseID: FBgn0030086
• Length: 535
• Species: Drosophila melanogaster
• Sequence 2: NP_012520.1
• Gene: CCT3 / 853438
• SGDID: S000003551
• Length: 534
• Species: Saccharomyces cerevisiae
• Alignment Length: 540
• Identity: 165/540 - (30%)
• Similarity: 288/540 - (53%)
• Gaps: 41/540 - (7%)

  Fly     7 PVRVLKNEAQEE-KAEMARLSSFIGAIAIGDLVKSTLGPKGMDKILVATGRNAGHVEVTNDGATI 70
            || |..|.:||. ....|::|:...|.|:.|::::.||||.|.|:|:..   .|.:.:||||..|
Yeast     4 PV-VFMNASQERTTGRQAQISNITAAKAVADVIRTCLGPKAMLKMLLDP---MGGLVLTNDGHAI 64

  Fly    71 LRAVGVDNPAAKILVDMSRVQDEEVGDGTTSVTVLASELLRE-AEKLVEQKLHPQIIVSGWRQAT 134
            ||.:.|.:||||.::::||.||||||||||:|.:||.|:|.: |..|:|:.:||.||:...::|.
Yeast    65 LREIDVAHPAAKSMLELSRTQDEEVGDGTTTVIILAGEILAQCAPYLIEKNIHPVIIIQALKKAL 129

  Fly   135 QVALEALTAAAQ----DNSSSDEKFRNDLLNIARTTLSSKILHQHKDFFANLAVDAVMRLKG--- 192
            ..|||.:...::    :|.::.:|       :.:.::.:|.:....:....||:|||..::.
Yeast   130 TDALEVIKQVSKPVDVENDAAMKK-------LIQASIGTKYVIHWSEKMCELALDAVKTVRKDLG 187

  Fly   193 ---SGE-------LKSIQIIKKSGGTLGDSFLDEGFLLDKKPGVH--QPQRIENARILIANTPMD 245
               .||       .:.:::.|..||.:.||.:.:|.||:|.. ||  ..:.|||.|:::.:.|::
Yeast   188 QTVEGEPNFEIDIKRYVRVEKIPGGDVLDSRVLKGVLLNKDV-VHPKMSRHIENPRVVLLDCPLE 251

  Fly   246 TDKIKVFGSS---IKVDSLAKIADLEMAEKEKMKEKVDKILKHKCNVFINRQLIYNYPEQLFADA 307
            ..|    |.|   |:::.......:...|:|:::...::||..:..:.|..:.:.:..:......
Yeast   252 YKK----GESQTNIEIEKEEDWNRILQIEEEQVQLMCEQILAVRPTLVITEKGVSDLAQHYLLKG 312

  Fly   308 RVMSIEHADFDGIERLAYCTGGEIVSTFENPSLVKLG-ECDVIEQVMIGEDTLLRFSGVKLGEAC 371
            ....:.........|:|..||..||:..|:.....:| .|.:.:..|||::........|..:||
Yeast   313 GCSVLRRVKKSDNNRIARVTGATIVNRVEDLKESDVGTNCGLFKVEMIGDEYFSFLDNCKEPKAC 377

  Fly   372 TIVIRGATQQILDEADRSLHDALCVLAATVKESRIIFGGGCSEALMATAVLKKAAETPGKEAIAI 436
            ||::||.::.||:|.||:|.||:.|....:....:..|||.:|..::..:.:||.:..|.:....
Yeast   378 TIMLRGGSKDILNEIDRNLQDAMAVARNVMLSPSLSPGGGATEMAVSVKLAEKAKQLEGIQQWPY 442

  Fly   437 EAFARALLSLPTAIADNAGYDSAQLVSELRAGHAQGKQTLGLDMELGKVADVRELGITESFAVKR 501
            :|.|.|:..:|..:..|||.|..:|:|:|||.||||..|.|:|.:.||:.|:...||.|...:|:
Yeast   443 QAVADAMECIPRTLIQNAGGDPIRLLSQLRAKHAQGNFTTGIDGDKGKIVDMVSYGIWEPEVIKQ 507

  Fly   502 QVLMSASEAAEMILRVDNII 521
            |.:.:|.|:|.::||||:|:
Yeast   508 QSVKTAIESACLLLRVDDIV 527

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCT2	NP_572524.1	TCP1_beta	10..527	CDD:239452	163/537 (30%)
CCT3	NP_012520.1	chap_CCT_gamma	4..533	CDD:274085	165/540 (31%)