Protein Alignment CCT2 and MKKS

DIOPT Version :9

• Sequence 1: NP_572524.1
• Gene: CCT2 / 31838
• FlyBaseID: FBgn0030086
• Length: 535
• Species: Drosophila melanogaster
• Sequence 2: NP_061336.1
• Gene: MKKS / 8195
• HGNCID: 7108
• Length: 570
• Species: Homo sapiens
• Alignment Length: 480
• Identity: 95/480 - (19%)
• Similarity: 186/480 - (38%)
• Gaps: 82/480 - (17%)

  Fly    37 LVKSTLGPKGMDKILVATGRN--AGHVEVTNDGATILRAVGVDNPAAKILVDMSRVQDEEVGDGT 99
            :|.|..||.|..|.|    .|  .|:|..|:..:.:|..:.|.:|..|||....:.......|..
Human    32 IVTSCYGPSGRLKQL----HNGFGGYVCTTSQSSALLSHLLVTHPILKILTASIQNHVSSFSDCG 92

  Fly   100 TSVTVLASELLREAEKLVEQKLHPQIIVSGWRQATQVALEALTAAA------QDNSSSDEKFRND 158
            ....:|...|:...::|   .|.|..::...:....:.:..|.:..      .|.||:     ..
Human    93 LFTAILCCNLIENVQRL---GLTPTTVIRLNKHLLSLCISYLKSETCGCRIPVDFSST-----QI 149

  Fly   159 LLNIARTTLSSK----ILHQHKDFFANLAVDAVM-----RLKGSGELKSIQIIKKSGGTLGDSFL 214
            ||.:.|:.|:||    :..:..:..:.|.:.|.:     ..:|...|....|:...|..:.||.:
Human   150 LLCLVRSILTSKPACMLTRKETEHVSALILRAFLLTIPENAEGHIILGKSLIVPLKGQRVIDSTV 214

  Fly   215 DEGFLLDKKPGVHQPQRIENARIL----------------IANTPMDTDK---IKVFGSSIKVDS 260
            ..|.|::.       ..::..|:|                ::....||.:   :..:|.|::...
Human   215 LPGILIEM-------SEVQLMRLLPIKKSTALKVALFCTTLSGDTSDTGEGTVVVSYGVSLENAV 272

  Fly   261 LAKIADLEMAEKEKMKEKVDKILKHKCNVFINRQLIYNYPEQLFADARVMSIEHADFDGIERLAY 325
            |.::.:|   .::.:.:.||.:|   |...|:..|     :|.....|:::|:......:|.|..
Human   273 LDQLLNL---GRQLISDHVDLVL---CQKVIHPSL-----KQFLNMHRIIAIDRIGVTLMEPLTK 326

  Fly   326 CTGGEIVSTFENPSLVKLGECDVIEQVMIGEDTLLRFSGVKLGEA--CTIVIRGATQQILDEADR 388
            .||.:.:.:..:......|.   ::.|...:.....|..:...||  |::::........||...
Human   327 MTGTQPIGSLGSICPNSYGS---VKDVCTAKFGSKHFFHLIPNEATICSLLLCNRNDTAWDELKL 388

  Fly   389 SLHDALCVLAATVKESRIIFGGGCSEALMATAVLKKAAETPGKEAI---------AIEAFARALL 444
            :...||.||..|:||...:.||||:|..:|..:..|....|  |:|         .::..|.|..
Human   389 TCQTALHVLQLTLKEPWALLGGGCTETHLAAYIRHKTHNDP--ESILKDDECTQTELQLIAEAFC 451

  Fly   445 SLPTAIADNAGYDSAQLVSELRAGH 469
            |...::..:..:|..:::::::.||
Human   452 SALESVVGSLEHDGGEILTDMKYGH 476

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCT2	NP_572524.1	PTZ00212	1..530	CDD:185514	95/480 (20%)
		TCP1_beta	10..527	CDD:239452	95/480 (20%)
MKKS	NP_061336.1	Cpn60_TCP1	29..569	CDD:278544	95/480 (20%)
		chaperonin_like	32..476	CDD:295468	93/478 (19%)
		Substrate-binding apical domain	198..370		32/192 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0459
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810