Protein Alignment CCT2 and TCP1

DIOPT Version :9

• Sequence 1: NP_572524.1
• Gene: CCT2 / 31838
• FlyBaseID: FBgn0030086
• Length: 535
• Species: Drosophila melanogaster
• Sequence 2: NP_110379.2
• Gene: TCP1 / 6950
• HGNCID: 11655
• Length: 556
• Species: Homo sapiens
• Alignment Length: 535
• Identity: 189/535 - (35%)
• Similarity: 308/535 - (57%)
• Gaps: 28/535 - (5%)

  Fly    21 EMARLSSFIGAIAIGDLVKSTLGPKGMDKILVATGRNAGHVEVTNDGATILRAVGVDNPAAKILV 85
            |..|..:.:.|.:|.::|||:|||.|:||:||   .:.|.|.:||||||||:.:.|::||||:|.
Human    15 ETIRSQNVMAAASIANIVKSSLGPVGLDKMLV---DDIGDVTITNDGATILKLLEVEHPAAKVLC 76

  Fly    86 DMSRVQDEEVGDGTTSVTVLASELLREAEKLVEQKLHPQIIVSGWRQATQVALEALTAAAQDNSS 150
            :::.:||:|||||||||.::|:|||:.|::||:||:||..::||:|.|.:.|:..:......|
Human    77 ELADLQDKEVGDGTTSVVIIAAELLKNADELVKQKIHPTSVISGYRLACKEAVRYINENLIVN-- 139

  Fly   151 SDEKFRNDLLNIARTTLSSKILHQHKDFFANLAVDAVMRLKGS---GE----LKSIQIIKKSGGT 208
            :||..|:.|:|.|:|::||||:..:.|||||:.||||:.:|.:   |:    :.|:.|:|..|.:
Human   140 TDELGRDCLINAAKTSMSSKIIGINGDFFANMVVDAVLAIKYTDIRGQPRYPVNSVNILKAHGRS 204

  Fly   209 LGDSFLDEGFLLDKKPGVH-QPQRIENARILIANTPMDTDKIKVFGSSIKVDSLAKIADLEMAEK 272
            ..:|.|..|:.|:...|.. .|:||.||:|...:..:...|:|: |..:.:....|:..:...|.
Human   205 QMESMLISGYALNCVVGSQGMPKRIVNAKIACLDFSLQKTKMKL-GVQVVITDPEKLDQIRQRES 268

  Fly   273 EKMKEKVDKILKHKCNVFINRQLIYNYPEQLFADARVMSIEHADFDGIERLAYCTGGEIVSTFEN 337
            :..||::.|||....||.:....|.:...:.|.:|..|::.......::|:|..:|..|:||..|
Human   269 DITKERIQKILATGANVILTTGGIDDMCLKYFVEAGAMAVRRVLKRDLKRIAKASGATILSTLAN 333

  Fly   338 P------SLVKLGECDVIEQVMIGEDTLLRFSGVKLGEACTIVIRGATQQILDEADRSLHDALCV 396
            .      ....||:.:.:.|..|.:|.|:.....|...:.:|::|||...:.||.:|||||||||
Human   334 LEGEETFEAAMLGQAEEVVQERICDDELILIKNTKARTSASIILRGANDFMCDEMERSLHDALCV 398

  Fly   397 LAATVKESRIIFGGGCSEALMATAVLKKAAETPGKEAIAIEAFARALLSLPTAIADNAGYDSAQL 461
            :...::...::.|||..||.::..:...|.....:|.:||..|||:||.:|..:|.||..||..|
Human   399 VKRVLESKSVVPGGGAVEAALSIYLENYATSMGSREQLAIAEFARSLLVIPNTLAVNAAQDSTDL 463

  Fly   462 VSELRAGHAQGK--------QTLGLDMELGKVADVRELGITESFAVKRQVLMSASEAAEMILRVD 518
            |::|||.|.:.:        :.:|||:..||..|.::.|:.|...||.:.|..|:|||..|||:|
Human   464 VAKLRAFHNEAQVNPERKNLKWIGLDLSNGKPRDNKQAGVFEPTIVKVKSLKFATEAAITILRID 528

  Fly   519 NIIRCAPRRRVPDRG 533
            ::|:..|..:....|
Human   529 DLIKLHPESKDDKHG 543

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCT2	NP_572524.1	PTZ00212	1..530	CDD:185514	188/530 (35%)
		TCP1_beta	10..527	CDD:239452	188/527 (36%)
TCP1	NP_110379.2	TCP1_alpha	9..535	CDD:239451	187/525 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0459
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG60896
OrthoDB	1	1.010	-	-		D205390at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.830