Protein Alignment CCT2 and Mkks

DIOPT Version :9

• Sequence 1: NP_572524.1
• Gene: CCT2 / 31838
• FlyBaseID: FBgn0030086
• Length: 535
• Species: Drosophila melanogaster
• Sequence 2: NP_001135418.1
• Gene: Mkks / 59030
• MGIID: 1891836
• Length: 570
• Species: Mus musculus
• Alignment Length: 589
• Identity: 130/589 - (22%)
• Similarity: 222/589 - (37%)
• Gaps: 114/589 - (19%)

  Fly    12 KNEAQEEKAEMARLSSFIGAIAIGDLVKSTLGPKGMDKILVATGRN--AGHVEVTNDGATILRAV 74
            |.|....:...:.||...|.||      |..||.|..|.|    .|  .|.|..|:..:.:||.:
Mouse    13 KTEPLTSEKVRSTLSVLKGVIA------SCYGPSGRLKQL----HNGLGGCVYTTSQSSALLRNL 67

  Fly    75 GVDNPAAKILVDMSRVQDEE--VGDGTTSVTVLASELLREAEKLVEQKLHPQIIVSGWRQATQVA 137
            .|.:|..|||.  |.||:..  ..|......:|...|:...::|   .|.|...:    :..:..
Mouse    68 SVTHPVLKILT--SSVQNHVSCFSDCGLFTAILCCNLIENIQRL---DLTPATAI----KLNKYL 123

  Fly   138 LEALTAAAQDNSSS-----DEKFRNDLLNIARTTLSSK----ILHQHKDFFANLAVDA-VMRLKG 192
            |...|:..:..:.|     |.:..:..|::..:.|:||    :..:..|....|.:.| ::.:..
Mouse   124 LSLCTSYLKSEACSCRIPVDFRSTHTFLSLVHSILTSKPACMLTRKETDHIGALILKAFLLTIPE 188

  Fly   193 SGEL-----KSIQIIKKSGGTLGDSFLDEGFLLDKKP----GVHQPQRIENARILIANTPMDTDK 248
            |.|.     ||| |:...|..:.||.:..|.|::...    .:...|:....|:.:..|.:..|
Mouse   189 STEERMVLGKSI-IVPLKGQRVTDSTVLPGLLIEASEVQLRRLLPTQKASGLRVALFCTSLSGD- 251

  Fly   249 IKVFGSSIKVDSLAKIADLEMAEKEKMKEKVDKILKHKCNVFINRQLIYNYPEQLFADARVMSIE 313
            ....|..:.|....  ..||.|..|::.....:::....::.:.:::|:...:|.|::..||:|:
Mouse   252 FSNAGEGVVVAHYQ--VSLENAVLEQLLNLGRRLVTDHVDLVLCQKVIHPSLKQFFSERHVMAID 314

  Fly   314 HADFDGIERLAYCTGGEIVSTFENPSL-VKLGECDVIEQVMIGEDTLLRFSGVKLGEA--CTIVI 375
            ......:|.|:..||...:.:. ||.: ...|....:.....|..   .|..:...||  ||:::
Mouse   315 RVGVTLMESLSKVTGATPIGSL-NPIVSTTYGSVKDVCSARFGSK---HFFHLLPNEATVCTLLL 375

  Fly   376 RGATQQILDEADRSLHDALCVLAATVKESRIIFGGGCSEALMATAVLKKA---AE--------TP 429
            ........:|...:...|:.||..|:||..::.||||:|..:|..|..|.   ||        |.
Mouse   376 CSRNDTAWEELKLTCQTAMHVLQLTIKEPWVLLGGGCTETHLAAYVRHKVHHEAEAIVRDDGCTQ 440

  Fly   430 GKEAIAIEAFARALLSLPTAIADNAGYDSAQLVSELRAGHAQGKQ-----------TL-----GL 478
            .|..:|.|||..||.|    :|.:..:|..:::.:.:.||....|           ||     ||
Mouse   441 AKLHVAAEAFCSALES----VAGSLEHDGGEILIDTKYGHLWSCQADSASVGNWSDTLSRCGCGL 501

  Fly   479 --------------------------DMELGKVADVRELGITESFAVKRQVLMSASEAAEMILRV 517
                                      ...||..:::    ..:.|..|...|..|.|.|.:||.:
Mouse   502 YNSQEELSWSVLRSTYHPFAPQTCLPQAALGSASNL----TVDCFTAKLSGLQVAVETANLILDL 562

  Fly   518 DNII 521
            ..:|
Mouse   563 SYVI 566

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCT2	NP_572524.1	PTZ00212	1..530	CDD:185514	130/589 (22%)
		TCP1_beta	10..527	CDD:239452	130/589 (22%)
Mkks	NP_001135418.1	Cpn60_TCP1	29..569	CDD:395068	126/573 (22%)
		Substrate-binding apical domain. /evidence=ECO:0000250|UniProtKB:Q9NPJ1	198..370		36/179 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0459
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810