DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CCT2 and Bbs10

DIOPT Version :9

Sequence 1:	NP_572524.1	Gene:	CCT2 / 31838	FlyBaseID:	FBgn0030086	Length:	535	Species:	Drosophila melanogaster
Sequence 2:	NP_001102756.1	Gene:	Bbs10 / 500832	RGDID:	1560748	Length:	713	Species:	Rattus norvegicus

Alignment Length:	441	Identity:	83/441 - (18%)
Similarity:	164/441 - (37%)	Gaps:	88/441 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 MARLSSFIGAIAIGDLVKS----TLGPKGMDKILVATGRNAGHVEVTNDGATILRAVGVDNPAAK 82
            ||...|...|:.:.:::::    .:||:|.   ||...:..|.|.::.||..:|.|:.:::|.|:
  Rat     1 MASQGSVTAALRVAEVLETIANRCVGPEGG---LVLCTKPTGEVLLSRDGGCLLEALHLEHPLAR 62

  Fly    83 ILVDMSRVQDEEVGDGTTSVTVLASELLR------EAEK-------LVEQKLHPQIIVSGWRQAT 134
            ::|.......::.|||..:..:....|||      |.||       :...:.|.:.... |:..:
  Rat    63 MIVACVSSHLKKTGDGAKTFIIFLCHLLRGLHAIGEKEKDSFTSEDIQSHERHWKNCCQ-WKSIS 126

  Fly   135 QVALEALT----------------AAAQDNSSSDEKFRNDLLNIARTTLSSKILHQHKDFFANLA 183
            :..|...|                :|...::......|..|..:.......::...:..|.:.|.
  Rat   127 RALLRFQTQTLGCIVDQHLSRHYLSAFSSSAEGRTLCRRSLELLLEPYFCGRVGRNNHRFISQLM 191

  Fly   184 VDAVMRLKG--SG----ELKSIQIIKKSGGTLG----DSFLDEGFLLDKKPGVHQPQRIENARIL 238
            .|.|.:...  ||    |......::.:.|..|    :|.:.:|.:|.:...|:.|.. ...|::
  Rat   192 CDYVFKCMACESGIEVFEFLDNCFVELNVGVTGLPVSESRIVDGLVLPRDFSVYCPAD-GGIRMV 255

  Fly   239 IANTPMDTDKIKVFGSS---IKVDSLAKIADLEMAEKEKMKEKVDKILKHKCNVFINRQLIYNYP 300
            |....:.    .:|.||   ..:||..:....:....::.|..::.:..|...:.::.   ...|
  Rat   256 IVTEILQ----PLFSSSSSEFVLDSETQFQASQSWIMDRTKTVMNHLRSHNVKLLLSS---VKQP 313

  Fly   301 EQLFADARVMSIEHADFDGIERLAYCTGGEIVSTFENPSLVKLGEC---DVIEQVMIGEDTLLRF 362
            :.:...||:.||.         :..|...|.||..:.  :..|..|   ::..|..|.:..|:||
  Rat   314 DLVTYCARLNSIS---------VVECLSSEEVSLVQR--ITGLSPCVLPELASQCHIADSALVRF 367

  Fly   363 -------SG--VKLGEACT-------IVIRGATQQILDEADRSLHDALCVL 397
                   ||  ..||...|       :|:.|....::.:.:.:.|.|..:|
  Rat   368 CKPLIVRSGRYAHLGLVSTCAFVPHCVVLCGPVLGLVQQHESAFHGAFKML 418

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CCT2	NP_572524.1	PTZ00212	1..530	CDD:185514	83/441 (19%)
CCT2	NP_572524.1	TCP1_beta	10..527	CDD:239452	83/441 (19%)
Bbs10	NP_001102756.1	chaperonin_like	7..>94	CDD:295468	21/89 (24%)
		Cpn60_TCP1	13..>424	CDD:278544	79/429 (18%)
		Glyco_tranf_GTA_type	<589..>673	CDD:299700
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0459
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900