Protein Alignment CCT2 and Cct6b

DIOPT Version :10

• Sequence 1: NP_572524.1
• Gene: CCT2 / 31838
• FlyBaseID: FBgn0030086
• Length: 535
• Species: Drosophila melanogaster
• Sequence 2: NP_001014250.1
• Gene: Cct6b / 363658
• RGDID: 1359453
• Length: 531
• Species: Rattus norvegicus
• Alignment Length: 537
• Identity: 146/537 - (27%)
• Similarity: 283/537 - (52%)
• Gaps: 39/537 - (7%)

  Fly     8 VRVLKNEAQEEKAEMARLSSFIGAIAIGDLVKSTLGPKGMDKILVATGRNAGHVEVTNDGATILR 72
            :::....|:..:::.|...:...|..:.|:::.:|||||..|:||:   .||.:::|.||..:|.
  Rat     4 IKIANPGAEVTRSQAALAVNICAARGLQDVLRPSLGPKGALKMLVS---GAGDIKLTKDGNVLLH 65

  Fly    73 AVGVDNPAAKILVDMSRVQDEEVGDGTTSVTVLASELLREAEKLVEQKLHPQIIVSGWRQATQVA 137
            .:.:.:|.|.|:..::..||...||||||..::..|||::|:..:.:.|||:||..|:..|...|
  Rat    66 EMQIQHPTASIIAKVAAAQDHITGDGTTSNVLIIGELLKQADLYISEGLHPRIIAEGFDVAKTKA 130

  Fly   138 LEALTAAAQDNSSSDEKFRND-LLNIARTTLSSKILHQHKDFFANLAVDAVMRLKGSG---ELKS 198
            ||.|     |.....::.:.: ||::|||:|.:|:..:..|......||:|:.::..|   :|..
  Rat   131 LEVL-----DKIKVQKEMKREMLLDVARTSLRTKVHTELADILTEAVVDSVLAIRRPGIPIDLFM 190

  Fly   199 IQIIKKSGGTLGDSFLDEGFLLDKKPGVHQP---QRIENARILIANTPMDTDKIKVFGSSIKVDS 260
            ::|::....:..|:.|..|.:||.  |...|   :::::|.|||.|..::.:|.:| .|.....:
  Rat   191 VEIVEMRHKSETDTQLVRGLVLDH--GARHPRMKKQVQDAYILICNVSLEYEKTEV-SSGFFYKT 252

  Fly   261 LAKIADLEMAEKEKMKEKVDKIL---------KHKCNVFINRQLIYNYPEQLFADARVMSIEHAD 316
            :.:...|..||::.::::|.||:         .:|..|.||::.|.....::.|...::::..|.
  Rat   253 VEEKEKLVKAERKFIEDRVQKIIDLKQKVCAESNKGFVVINQKGIDPVSLEMLAKHNIVALRRAK 317

  Fly   317 FDGIERLAYCTGGEIVSTFENPSLVKLGECDVIEQVMIGEDTLLRFSGVKLGEAC------TIVI 375
            ...:|||....||..|::.|:.|...||...::.:..:||:   :|:.:   |.|      |:::
  Rat   318 RRNLERLTLACGGLAVNSLEDLSEECLGHAGLVFEYTLGEE---KFTFI---EDCVNPLSVTLLV 376

  Fly   376 RGATQQILDEADRSLHDALCVLAATVKESRIIFGGGCSEALMATAVLKKAAETPGKEAIAIEAFA 440
            :|..:..|.:...:|.|.|..:...:::..::.|.|..|..:|.|::.......|:..:.|:|||
  Rat   377 KGPNKHTLIQIKDALRDGLRAVKNAIEDGCVVPGAGAVEVAIAEALVNYKHCVQGRARLGIQAFA 441

  Fly   441 RALLSLPTAIADNAGYDSAQLVSELRAGHAQGKQTLGLDMELGKVADVRELGITESFAVKRQVLM 505
            .|||.:|..:|.|:|||..:.:.:::..||:.|:.:|:|:..|:.....|.||.:::.||:.:|.
  Rat   442 DALLIIPKVLAQNSGYDLQETLIKIQTKHAESKELVGIDLNTGEPMVAAEAGIWDNYCVKKHILH 506

  Fly   506 SASEAAEMILRVDNIIR 522
            |.:..|..:|.||.|:|
  Rat   507 SCTVIATNVLLVDEIMR 523

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCT2	NP_572524.1	TCP1_beta	10..527	CDD:239452	146/535 (27%)
Cct6b	NP_001014250.1	chap_CCT_zeta	3..530	CDD:274088	146/537 (27%)