Protein Alignment CCT2 and HSPD1

DIOPT Version :9

• Sequence 1: NP_572524.1
• Gene: CCT2 / 31838
• FlyBaseID: FBgn0030086
• Length: 535
• Species: Drosophila melanogaster
• Sequence 2: NP_002147.2
• Gene: HSPD1 / 3329
• HGNCID: 5261
• Length: 573
• Species: Homo sapiens
• Alignment Length: 564
• Identity: 135/564 - (23%)
• Similarity: 238/564 - (42%)
• Gaps: 108/564 - (19%)

  Fly    23 ARLSSFIGAIAIGDLVKSTLGPKGMDKILVATGRNAGHVEVTNDGATILRAVGV----DNPAAKI 83
            ||.....|...:.|.|..|:||||...|:   .::.|..:||.||.|:.:::.:    .|..||:
Human    36 ARALMLQGVDLLADAVAVTMGPKGRTVII---EQSWGSPKVTKDGVTVAKSIDLKDKYKNIGAKL 97

  Fly    84 LVDMSRVQDEEVGDGTTSVTVLASELLREAEKLVEQKLHPQIIVSGWRQATQVALEALTAAAQDN 148
            :.|::...:||.|||||:.||||..:.:|..:.:.:..:|..|    |:...:|::|:.|..:..
Human    98 VQDVANNTNEEAGDGTTTATVLARSIAKEGFEKISKGANPVEI----RRGVMLAVDAVIAELKKQ 158

  Fly   149 S---SSDEKFRNDLLNIARTTLSSKILHQHKDFFANLAVDAVMRLKGSGELKSIQIIKKSGGTLG 210
            |   ::.|    ::..:|  |:|:   :..|: ..|:..||:.::...|     .|..|.|.||.
Human   159 SKPVTTPE----EIAQVA--TISA---NGDKE-IGNIISDAMKKVGRKG-----VITVKDGKTLN 208

  Fly   211 DSF-LDEGFLLDKKPGVHQPQRIENARILIANTPMDTDKIKVFGSSIKVDSLAKIAD-LEMAEKE 273
            |.. :.||...|:  |...|..|..::    ....:.....|..|..|:.|:..|.. ||:|...
Human   209 DELEIIEGMKFDR--GYISPYFINTSK----GQKCEFQDAYVLLSEKKISSIQSIVPALEIANAH 267

  Fly   274 K-----MKEKVDKILKHKCNVFINRQLIYNYPEQLFADARVMSIEHADF-----DGIERLAYCTG 328
            :     :.|.||.  :....:.:||         |....:|::::...|     :.::.:|..||
Human   268 RKPLVIIAEDVDG--EALSTLVLNR---------LKVGLQVVAVKAPGFGDNRKNQLKDMAIATG 321

  Fly   329 ------------------------GEIVSTFENPSLVKLGECD----------VIEQVMIG---- 355
                                    ||::.|.::..|:| |:.|          :|||:.:.
Human   322 GAVFGEEGLTLNLEDVQPHDLGKVGEVIVTKDDAMLLK-GKGDKAQIEKRIQEIIEQLDVTTSEY 385

  Fly   356 EDTLLRFSGVKLGEACTIVIRGATQQI-LDEADRSLHDALCVLAATVKESRIIFGGGCSEALMAT 419
            |...|.....||.:...::..|.|..: ::|....:.|||....|.|:|. |:.||||:   :..
Human   386 EKEKLNERLAKLSDGVAVLKVGGTSDVEVNEKKDRVTDALNATRAAVEEG-IVLGGGCA---LLR 446

  Fly   420 AVLKKAAETPGKE--AIAIEAFARALLSLPTAIADNAGYDSAQLVSELRAGHAQGKQTLGLDMEL 482
            .:....:.||..|  .|.||...|.|......||.|||.:.:.:|.::    .|....:|.|...
Human   447 CIPALDSLTPANEDQKIGIEIIKRTLKIPAMTIAKNAGVEGSLIVEKI----MQSSSEVGYDAMA 507

  Fly   483 GKVADVRELGITESFAVKRQVLMSASEAAEMILRVDNIIRCAPR 526
            |...::.|.||.:...|.|..|:.|:..|.::...:.::...|:
Human   508 GDFVNMVEKGIIDPTKVVRTALLDAAGVASLLTTAEVVVTEIPK 551

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCT2	NP_572524.1	PTZ00212	1..530	CDD:185514	135/564 (24%)
		TCP1_beta	10..527	CDD:239452	135/564 (24%)
HSPD1	NP_002147.2	GroEL	28..548	CDD:239460	134/559 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0459
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810