Protein Alignment CCT2 and Mkks

DIOPT Version :10

• Sequence 1: NP_572524.1
• Gene: CCT2 / 31838
• FlyBaseID: FBgn0030086
• Length: 535
• Species: Drosophila melanogaster
• Sequence 2: NP_001008354.1
• Gene: Mkks / 311456
• RGDID: 1308814
• Length: 570
• Species: Rattus norvegicus
• Alignment Length: 604
• Identity: 128/604 - (21%)
• Similarity: 221/604 - (36%)
• Gaps: 144/604 - (23%)

  Fly    12 KNEAQEEKAEMARLSSFIGAIAIGDLVKSTLGPKGMDKILVATGRN--AGHVEVTNDGATILRAV 74
            |.|....:...:.||...|.||      |..||.|..|.|    .|  .|.|..|:..:.:||.:
  Rat    13 KTEPLTSERVRSTLSVLKGIIA------SCYGPSGRLKQL----HNGLGGCVCTTSQSSALLRNL 67

  Fly    75 GVDNPAAKILVDMSRVQDEE--VGDGTTSVTVLASELLREAEKLVEQKLHPQIIVSGWRQATQVA 137
            .|.:|..|:|.  |.||:..  ..|......:|...|:...:::   .|.|...:...:....::
  Rat    68 SVTHPILKVLT--SSVQNHVCCFSDCGLFTAILCCNLIENIQRI---GLTPTTAIKLNKYLLGLS 127

  Fly   138 LEAL-TAAAQDNSSSDEKFRNDLLNIARTTLSSK----ILHQHKDFFANLAVDA-VMRLKGSGEL 196
            :..| :.|.......|.:..:..||:..:.|:||    :..:..|....|.:.| ::.:..|.|.
  Rat   128 ISYLKSEACSCRIPVDFRSTHTFLNLVHSILTSKPACMLTRKEIDHIGALILKAFLLTIPESAEE 192

  Fly   197 -----KSIQIIKKSGGTLGDSFLDEGFLLDKKPGVHQPQRIENARILIANTPMDTDKIKVFGSSI 256
                 ||| |:...|..:.||.:..|.|::...        ...|.|:......|.::.:|.:|:
  Rat   193 RMVLGKSI-IVPLKGQQVTDSTVLPGLLIEASE--------VQLRRLLPTQKSSTLRVALFCASL 248

  Fly   257 KVD---------------SL--AKIADLEMAEKEKMKEKVDKILKHKCNVFINRQLIYNYPEQLF 304
            ..|               ||  |.:..|....::.:.:.||.:|   |...|:..|     :|..
  Rat   249 SGDFSNAGEGTLVVHYQVSLENAVLEQLLNLGRQLVSDHVDLVL---CQKVIHPSL-----KQFL 305

  Fly   305 ADARVMSIEHADFDGIERLAYCTGG-------EIVSTFENPSLVKLGECDVIEQVMIGEDTLLRF 362
            ::.::::|:......:|.|:..||.       .||||       ..|....:.....|..   .|
  Rat   306 SEHQIIAIDRVGVTLMEPLSKVTGATPIGSLYPIVST-------TYGSVKDVRSARFGSK---YF 360

  Fly   363 SGVKLGEA--CTIVIRGATQQILDEADRSLHDALCVLAATVKESRIIFGGGCSEALMAT------ 419
            ..:...||  |::::........:|...:...|:.||..|:||..::.||||.|..:|.
  Rat   361 FHLLPNEATICSLLLCSRNDTAWEELKLTCQTAMHVLQLTIKEPWVLLGGGCVETHLAAYIRHKV 425

  Fly   420 -----AVLKKAAETPGKEAIAIEAFARALLSLPTAIADNAGYDSAQLVSELRAGH---------- 469
                 |:::....:..:..||.|||..||.|...::.    :|..:::.:::.||
  Rat   426 HNEAEAIVRDDGCSQAELHIATEAFCSALESAAVSLE----HDGGEILIDMKYGHFWSCPADSAS 486

  Fly   470 -AQGKQTL-----GL---DMEL-----------------------GKVADVRELGITESFAVKRQ 502
             .....||     ||   ..||                       |.|:::    ..:||..|..
  Rat   487 VGNWPDTLSRCGCGLYNSQEELSWSVLRSTYHPFAPQTCLPQAASGSVSNL----TVDSFTAKLS 547

  Fly   503 VLMSASEAAEMILRVDNII 521
            .|..|.|.|.:||.:..:|
  Rat   548 GLQVAVETANLILDLSYVI 566

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCT2	NP_572524.1	TCP1_beta	10..527	CDD:239452	128/604 (21%)
Mkks	NP_001008354.1	Cpn60_TCP1	29..569	CDD:395068	124/588 (21%)