Protein Alignment CCT2 and Cct4

DIOPT Version :10

• Sequence 1: NP_572524.1
• Gene: CCT2 / 31838
• FlyBaseID: FBgn0030086
• Length: 535
• Species: Drosophila melanogaster
• Sequence 2: NP_877966.1
• Gene: Cct4 / 29374
• RGDID: 727937
• Length: 539
• Species: Rattus norvegicus
• Alignment Length: 516
• Identity: 170/516 - (32%)
• Similarity: 292/516 - (56%)
• Gaps: 19/516 - (3%)

  Fly    18 EKAEMARLSSFIGAIAIGDLVKSTLGPKGMDKILVATGRNAGHVEVTNDGATILRAVGVDNPAAK 82
            :|....|.|:...|.|:.|.::::|||||||| ::..|:  |.|.:||||||||:.:.|.:|||:
  Rat    28 DKPAQIRFSNISAAKAVADAIRTSLGPKGMDK-MIQDGK--GDVTITNDGATILKQMQVLHPAAR 89

  Fly    83 ILVDMSRVQDEEVGDGTTSVTVLASELLREAEKLVEQKLHPQIIVSGWRQATQVALEALTAAAQD 147
            :||::|:.||.|.|||||||.::|..||....||:::.:||.||...:::|.:..||.||..::.
  Rat    90 MLVELSKAQDIEAGDGTTSVVIIAGSLLDSCTKLLQKGIHPTIISESFQKALEKGLEILTDMSRP 154

  Fly   148 NSSSDEKFRNDLLNIARTTLSSKILHQHKDFFANLAVDAVMRL-----KGSGELKSIQIIKKSGG 207
            ...||   |..|||.|.|:|:||::.|:....:.::|:|||::     ..|.:|:.|:|:||.||
  Rat   155 VQLSD---RETLLNSATTSLNSKVVSQYSSLLSPMSVNAVMKVIDPATATSVDLRDIKIVKKLGG 216

  Fly   208 TLGDSFLDEGFLLDKKPGVHQPQRIENARILIANTPMDTDKIKVFGSSIKVDSLAKIADLEMAEK 272
            |:.|..|.||.:|.:|.......|:|.|:|.:....:...|..: .:.|.|...|::..:...|:
  Rat   217 TIDDCELVEGLVLTQKVANSGITRVEKAKIGLIQFCLSAPKTDM-DNQIVVSDYAQMDRVLREER 280

  Fly   273 EKMKEKVDKILKHKCNVF-----INRQLIYNYPEQLFADARVMSIEHADFDGIERLAYCTGGEIV 332
            ..:...|.:|.|..|||.     |.|..:.:.........::|.::..:.:.||.:....|.:.|
  Rat   281 AYILNLVKQIKKTGCNVLLIQKSILRDALSDLALHFLNKMKIMVVKDIEREDIEFICKTIGTKPV 345

  Fly   333 STFENPSLVKLGECDVIEQVMI-GEDTLLRFSG-VKLGEACTIVIRGATQQILDEADRSLHDALC 395
            :..:..:...||..::.|:|.: |...|.:.:| ...|:..|||:||:.:.:::||:||:|||||
  Rat   346 AHIDQFTPDMLGSAELAEEVSLNGSGKLFKITGCTSPGKTVTIVVRGSNKLVIEEAERSIHDALC 410

  Fly   396 VLAATVKESRIIFGGGCSEALMATAVLKKAAETPGKEAIAIEAFARALLSLPTAIADNAGYDSAQ 460
            |:...||:..:|.|||..|..:|..:.:.:....|.|:..:.|||.|:..:|:.:|:|||.:...
  Rat   411 VIRCLVKKRALIAGGGAPEIELALRLTEYSRTLSGMESYCVRAFADAMEVIPSTLAENAGLNPIS 475

  Fly   461 LVSELRAGHAQGKQTLGLDMELGKVADVRELGITESFAVKRQVLMSASEAAEMILRVDNII 521
            .|:|||..||||::|.|:::..|.::::.|..:.:...|....|..|:|....||::|:::
  Rat   476 TVTELRNRHAQGEKTTGINVRKGGISNILEEMVVQPLLVSVSALTLATETVRSILKIDDVV 536

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCT2	NP_572524.1	TCP1_beta	10..527	CDD:239452	170/516 (33%)
Cct4	NP_877966.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..28		170/516 (33%)
		TCP1_delta	25..538	CDD:239454	170/516 (33%)