Protein Alignment CCT2 and cct4

DIOPT Version :10

• Sequence 1: NP_572524.1
• Gene: CCT2 / 31838
• FlyBaseID: FBgn0030086
• Length: 535
• Species: Drosophila melanogaster
• Sequence 2: NP_595155.1
• Gene: cct4 / 2540053
• PomBaseID: SPBC106.06
• Length: 527
• Species: Schizosaccharomyces pombe
• Alignment Length: 518
• Identity: 186/518 - (35%)
• Similarity: 300/518 - (57%)
• Gaps: 24/518 - (4%)

  Fly    18 EKAEMARLSSFIGAIAIGDLVKSTLGPKGMDKILVATGRNAGHVEVTNDGATILRAVGVDNPAAK 82
            ||.:..|||:.:.|.::.|.::::|||||||| ::.||:  |.|.:||||||||:.:.|.:||||
pombe    15 EKPQEVRLSNIMAARSVADAIRTSLGPKGMDK-MIQTGK--GEVILTNDGATILKHLSVLHPAAK 76

  Fly    83 ILVDMSRVQDEEVGDGTTSVTVLASELLREAEKLVEQKLHPQIIVSGWRQATQVALEALTAAAQD 147
            :|||:|..||.|.|||||||.:||..:|..||||:::.:||.:|...:::|....::.:...|..
pombe    77 MLVDLSAAQDVEAGDGTTSVVILAGSMLACAEKLLKKGIHPTVIAESFQRAAGFTVDCMKENALA 141

  Fly   148 NSSSDEKFRNDLLNIARTTLSSKILHQHKDFFANLAVDAVM-----RLKGSGELKSIQIIKKSGG 207
            ...||   |..||..|.|:|:|||:.|:.:..|.:|||||:     |:..:.:||.|:|:||.||
pombe   142 IELSD---RESLLRAATTSLNSKIVSQYSNLLAPIAVDAVLKVIDPRVATNVDLKDIRIVKKLGG 203

  Fly   208 TLGDSFLDEGFLLD----KKPGVHQPQRIENARILIANTPMDTDKIKVFGSSIKVDSLAKIADLE 268
            .:.|:.|..|..|.    |..|  .|.|||.|.|.:....:...|..: .:.:.|:...::..:.
pombe   204 IIDDTELIPGLALTQTAVKSAG--GPTRIEKANIALIQFQLSPPKPDM-ENQVVVNDYRQMDKIL 265

  Fly   269 MAEKEKMKEKVDKILKHKCNVF-----INRQLIYNYPEQLFADARVMSIEHADFDGIERLAYCTG 328
            ..|::.:.....||.|...||.     |.|..:.:......|..::|.|:..:.|.:|.:...||
pombe   266 KEERQYLLNMCKKIKKAGANVILIQKSILRDAVNDLALHFLAKLKIMVIKDIERDEVEFICKSTG 330

  Fly   329 GEIVSTFENPSLVKLGECDVIEQVMIGEDTLLRFSGVK-LGEACTIVIRGATQQILDEADRSLHD 392
            .:.::..|:.:..|||..|::|:.....:.:::||||| .|:..:|:.|||....|:||:|||||
pombe   331 CKPIADIESFAEDKLGHADLVEETSSSGEKIVKFSGVKNAGKTVSILCRGANLLTLEEAERSLHD 395

  Fly   393 ALCVLAATVKESRIIFGGGCSEALMATAVLKKAAETPGKEAIAIEAFARALLSLPTAIADNAGYD 457
            ||||:...||:..:|.|||..|...|..:|:.|.:..|:|||.|.||:.||..:|..:|:|||.:
pombe   396 ALCVIRCLVKQRALIAGGGSPEIEAAQRLLEHARQLEGREAICIRAFSEALEIIPVTLAENAGLN 460

  Fly   458 SAQLVSELRAGHAQGKQTLGLDMELGKVADVRELGITESFAVKRQVLMSASEAAEMILRVDNI 520
            :.|:|:|||:.||.|::|.|:::..|.|.::.|..:.:...|....:..|:|..:||:::|:|
pombe   461 AIQVVTELRSRHANGEKTAGINVRKGIVTNILEENVLQPLLVNISAIQLAAETTKMIMKIDDI 523

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCT2	NP_572524.1	TCP1_beta	10..527	CDD:239452	186/518 (36%)
cct4	NP_595155.1	TCP1_delta	12..526	CDD:239454	186/518 (36%)