Protein Alignment CCT2 and cct1

DIOPT Version :10

• Sequence 1: NP_572524.1
• Gene: CCT2 / 31838
• FlyBaseID: FBgn0030086
• Length: 535
• Species: Drosophila melanogaster
• Sequence 2: NP_595949.1
• Gene: cct1 / 2539691
• PomBaseID: SPBC12D12.03
• Length: 556
• Species: Schizosaccharomyces pombe
• Alignment Length: 546
• Identity: 189/546 - (34%)
• Similarity: 303/546 - (55%)
• Gaps: 50/546 - (9%)

  Fly    21 EMARLSSFIGAIAIGDLVKSTLGPKGMDKILVATGRNAGHVEVTNDGATILRAVGVDNPAAKILV 85
            |..|..:.:...||.::|||:|||.|:||:||   .:.|.|.|||||||||..:.|::||.|:||
pombe    20 EDVRNQNVLATTAIANVVKSSLGPVGLDKMLV---DDIGDVTVTNDGATILSLLDVEHPAGKVLV 81

  Fly    86 DMSRVQDEEVGDGTTSVTVLASELLREAEKLVEQKLHPQIIVSGWRQATQVALEALTAAAQDNSS 150
            ::::.||:|||||||||.::|:||||.|.:||:.|:||..|::|:|.|.:.|::.:|...  :.|
pombe    82 ELAQQQDKEVGDGTTSVVIIAAELLRRANELVKNKIHPTTIITGYRLAIREAVKFMTDVL--SCS 144

  Fly   151 SDEKFRNDLLNIARTTLSSKILHQHKDFFANLAVDAVMRLKGS---GE----LKSIQIIKKSGGT 208
            .|...:..|:|:|:|::||||:....|||:.:||||::.:|.|   ||    :|::.|:|..|.:
pombe   145 VDSLGKESLINVAKTSMSSKIIGNDSDFFSTMAVDAMLSVKTSNSKGETRYPVKAVNILKAHGKS 209

  Fly   209 LGDSFLDEGFLLD-KKPGVHQPQRIENARILIANTPMDTDKIKV-FGSSIKV---DSLAKIADLE 268
            ..:|.|.:|:.|: .........|::||:|.:.:  ||..|.|: .|..:.:   |.|.||
pombe   210 SRESVLVKGYALNCTIASQAMKTRVQNAKIAVLD--MDLQKTKMALGVHVTIDDPDQLEKI---- 268

  Fly   269 MAEKEKM--KEKVDKILKHKCNVFINRQLIYNYPEQLFADARVMSIEHADFDGIERLAYCTGGEI 331
             .|:|.|  .|:|.|||....||.:..:.|.:...:...:|..|::.....:.:.|:|..:|..:
pombe   269 -REREVMITLERVKKILNAGANVILTTKGIDDLCLKSIIEAGAMAVRRCKKEDLRRIAKASGATL 332

  Fly   332 VS---------TFENPSLVKLGECDVIEQVMIGEDTLLRFSGVKLGEACTIVIRGATQQILDEAD 387
            :|         |||:.   .||..:.:.|....:|..:...|.|...:.:||:||..:..|||.:
pombe   333 LSSLSNLEGEETFESS---YLGSAEEVVQEKFSDDECILVKGTKAYSSASIVLRGPNEYSLDEME 394

  Fly   388 RSLHDALCVLAATVKESRIIFGGGCSEALMATAVLKKAAETPGKEAIAIEAFARALLSLPTAIAD 452
            ||:||:|.|:..|::..:::.|||..|..::..:...|.....:|.:||..||:|||.:|..:|.
pombe   395 RSMHDSLSVVKRTLESGKVVPGGGAVETALSIYLENFATSLGSREQLAIAEFAQALLIIPRTLAV 459

  Fly   453 NAGYDSAQLVSELRAGHA------------QGKQTLGLDMELGKVADVRELGITESFAVKRQVLM 505
            ||..||.:|.::|||.||            :|.:..|||:..|.:.|..:.|:.|....|.:.|.
pombe   460 NAAKDSTELTAKLRAYHAASQNAEVTDVKKRGYKNYGLDLLNGVIRDNVKAGVLEPSMSKLKSLK 524

  Fly   506 SASEAAEMILRVDNIIRCAPRRRVPD 531
            ||.||...|||:|..|:..|.|:..|
pombe   525 SAVEACIAILRIDTSIKLDPERQPED 550

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCT2	NP_572524.1	TCP1_beta	10..527	CDD:239452	187/540 (35%)
cct1	NP_595949.1	TCP1_alpha	14..544	CDD:239451	186/538 (35%)