Protein Alignment CCT2 and CCT5

DIOPT Version :10

• Sequence 1: NP_572524.1
• Gene: CCT2 / 31838
• FlyBaseID: FBgn0030086
• Length: 535
• Species: Drosophila melanogaster
• Sequence 2: NP_036205.1
• Gene: CCT5 / 22948
• HGNCID: 1618
• Length: 541
• Species: Homo sapiens
• Alignment Length: 528
• Identity: 180/528 - (34%)
• Similarity: 300/528 - (56%)
• Gaps: 23/528 - (4%)

  Fly     7 PVRVLKNEAQEEKAEMARL----SSFIGAIAIGDLVKSTLGPKGMDKILVATGRNAGHVEVTNDG 67
            |..::|:  |:.|:.:..|    |..:.|.|:.:.::::|||.|:||::|   ...|.|.|||||
Human    15 PFLIIKD--QDRKSRLMGLEALKSHIMAAKAVANTMRTSLGPNGLDKMMV---DKDGDVTVTNDG 74

  Fly    68 ATILRAVGVDNPAAKILVDMSRVQDEEVGDGTTSVTVLASELLREAEKLVEQKLHPQIIVSGWRQ 132
            ||||..:.||:..||::|::|:.||:|:|||||.|.|||..||.|||:|:::.:||..|..|:.|
Human    75 ATILSMMDVDHQIAKLMVELSKSQDDEIGDGTTGVVVLAGALLEEAEQLLDRGIHPIRIADGYEQ 139

  Fly   133 ATQVALEALTAAAQDNSSSDEKFRNDLLNIARTTLSSKILHQHKDFFANLAVDAVMRL----KGS 193
            |.:||:|.|...: |:...|.|....|:..|:|||.||:::......|.:||:||:.:    :..
Human   140 AARVAIEHLDKIS-DSVLVDIKDTEPLIQTAKTTLGSKVVNSCHRQMAEIAVNAVLTVADMERRD 203

  Fly   194 GELKSIQIIKKSGGTLGDSFLDEGFLLDKKPGVHQ-PQRIENARILIANTPMDTDKIKVFGSSIK 257
            .:.:.|::..|.||.|.|:.|.:|.::||.....| |:::|:|:|.|...|.:..|.|. ...:.
Human   204 VDFELIKVEGKVGGRLEDTKLIKGVIVDKDFSHPQMPKKVEDAKIAILTCPFEPPKPKT-KHKLD 267

  Fly   258 VDSLAKIADLEMAEKEKMKEKVDKILKHKCNVFINRQLIYNYPEQLFADARVMSIEHADFDGIER 322
            |.|:.....|:..||||.:|.:.:|.:...|:.|.:....:....|.....:.::.......||.
Human   268 VTSVEDYKALQKYEKEKFEEMIQQIKETGANLAICQWGFDDEANHLLLQNNLPAVRWVGGPEIEL 332

  Fly   323 LAYCTGGEIVSTFENPSLVKLGECDVIEQVMIG--EDTLLRFSGVKLGEACTIVIRGATQQILDE 385
            :|..|||.||..|...:..|||...:::::..|  :|.:|.....|...|.||.|||..:.|::|
Human   333 IAIATGGRIVPRFSELTAEKLGFAGLVQEISFGTTKDKMLVIEQCKNSRAVTIFIRGGNKMIIEE 397

  Fly   386 ADRSLHDALCVLAATVKESRIIFGGGCSEALMATAVLKKAAETPGKEAIAIEAFARALLSLPTAI 450
            |.|||||||||:...::::|:::|||.:|...|.||.::|.:.|..|..|:.|||.||..:|.|:
Human   398 AKRSLHDALCVIRNLIRDNRVVYGGGAAEISCALAVSQEADKCPTLEQYAMRAFADALEVIPMAL 462

  Fly   451 ADNAGYDSAQLVSELRAGHAQGKQ---TLGLDMELGKVADVRELGITESFAVKRQVLMSASEAAE 512
            ::|:|.:..|.::|:||  .|.|:   .||:|.......|:::..:.|:...|:|.:..|::...
Human   463 SENSGMNPIQTMTEVRA--RQVKEMNPALGIDCLHKGTNDMKQQHVIETLIGKKQQISLATQMVR 525

  Fly   513 MILRVDNI 520
            |||::|:|
Human   526 MILKIDDI 533

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCT2	NP_572524.1	TCP1_beta	10..527	CDD:239452	179/525 (34%)
CCT5	NP_036205.1	TCP1_epsilon	10..535	CDD:239455	180/528 (34%)