Protein Alignment CCT2 and cct-4

DIOPT Version :10

• Sequence 1: NP_572524.1
• Gene: CCT2 / 31838
• FlyBaseID: FBgn0030086
• Length: 535
• Species: Drosophila melanogaster
• Sequence 2: NP_495750.1
• Gene: cct-4 / 174330
• WormBaseID: WBGene00000379
• Length: 540
• Species: Caenorhabditis elegans
• Alignment Length: 528
• Identity: 184/528 - (34%)
• Similarity: 291/528 - (55%)
• Gaps: 30/528 - (5%)

  Fly    12 KNEAQEEKAEMARLSSFIGAIAIGDLVKSTLGPKGMDKILVATGRNAGHVEVTNDGATILRAVGV 76
            :|...::|.|..|.|:.:.|.|:.|.|:::|||:|||| ::.:|.  |.|.:||||||||..:.|
 Worm    21 RNFKDKDKPESVRNSNIVAAKAVADAVRTSLGPRGMDK-MIQSGN--GDVTITNDGATILNQMSV 82

  Fly    77 DNPAAKILVDMSRVQDEEVGDGTTSVTVLASELLREAEKLVEQKLHPQIIVSGWRQATQVALEAL 141
            .:|.||:||::|:.||.|.|||||:|.|:|..||..|:.|:.:.:||..|...::.|...|.:.|
 Worm    83 IHPTAKMLVELSKAQDIEAGDGTTTVVVMAGALLDAAQNLLSKGIHPTTISESFQSAAAEAEKIL 147

  Fly   142 TAAAQDNSSSDEKFRND-LLN-IARTTLSSKILHQHKDFFANLAVDAVMRLKGSG-----ELKSI 199
                 |..||.....|| ||| :|.|:|:||::.||....|.:||:||.::..|.     .||.|
 Worm   148 -----DEMSSPVDLSNDALLNKMATTSLNSKVVSQHSWLLAPMAVNAVKKIINSENDSNVNLKMI 207

  Fly   200 QIIKKSGGTLGDSFLDEGFLLDKKP-GVHQPQRIENARILIANTPMDTDKIKVFGSSIKVDSLAK 263
            :||||.|.|:.:|.|.||.|:|:|. |...|.|||.|:|.:....:...|..:....|..|
 Worm   208 KIIKKMGDTVEESELIEGALIDQKTMGRGAPTRIEKAKIGLIQFQISPPKTDMENQVIITD---- 268

  Fly   264 IADLEMAEKEK---MKEKVDKILKHKCNV-FINRQLIYNYPEQL----FADARVMSIEHADFDGI 320
            .|.::.|.||:   :.|...:|....||| .|.:.::.:...:|    .|..::|.|:..:.:.|
 Worm   269 YAQMDRALKEERQYLLEICKQIKAAGCNVLLIQKSILRDAVNELALHFLAKMKIMCIKDIEREDI 333

  Fly   321 ERLAYCTGGEIVSTFENPSLVKLGECDVIEQVMIGED-TLLRFSGVK-LGEACTIVIRGATQQIL 383
            |..:...|...|::.::.:...||..|::|::..|.| .:::.:||: .|.|.:|::||:.:.:|
 Worm   334 EFYSRILGCRPVASVDHFNADALGYADLVEEIPTGGDGKVIKVTGVQNPGHAVSILLRGSNKLVL 398

  Fly   384 DEADRSLHDALCVLAATVKESRIIFGGGCSEALMATAVLKKAAETPGKEAIAIEAFARALLSLPT 448
            :|||||:||||||:...||:..::.|||..|..:|..:...|....|.......|||.||..:|.
 Worm   399 EEADRSIHDALCVIRCLVKKKALLPGGGAPEMEIAVKLRNLAQTQHGATQYCWRAFADALELIPY 463

  Fly   449 AIADNAGYDSAQLVSELRAGHAQGKQTLGLDMELGKVADVRELGITESFAVKRQVLMSASEAAEM 513
            .:|:|||......|:|||..||.|..:.|:::..|.|.|:.|..:.:...|....:..|||....
 Worm   464 TLAENAGLSPIHTVTELRNNHANGNSSYGVNVRKGYVTDMVEEDVVQPLLVTASAIKQASECVRS 528

  Fly   514 ILRVDNII 521
            ||::|:|:
 Worm   529 ILKIDDIV 536

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCT2	NP_572524.1	TCP1_beta	10..527	CDD:239452	184/528 (35%)
cct-4	NP_495750.1	chap_CCT_delta	23..539	CDD:274083	183/526 (35%)