Protein Alignment CCT2 and Hspd1

DIOPT Version :10

• Sequence 1: NP_572524.1
• Gene: CCT2 / 31838
• FlyBaseID: FBgn0030086
• Length: 535
• Species: Drosophila melanogaster
• Sequence 2: NP_034607.3
• Gene: Hspd1 / 15510
• MGIID: 96242
• Length: 573
• Species: Mus musculus
• Alignment Length: 564
• Identity: 140/564 - (24%)
• Similarity: 240/564 - (42%)
• Gaps: 108/564 - (19%)

  Fly    23 ARLSSFIGAIAIGDLVKSTLGPKGMDKILVATGRNAGHVEVTNDGATILRAVGV----DNPAAKI 83
            ||.....|...:.|.|..|:||||...|:   .::.|..:||.||.|:.:::.:    .|..||:
Mouse    36 ARALMLQGVDLLADAVAVTMGPKGRTVII---EQSWGSPKVTKDGVTVAKSIDLKDKYKNIGAKL 97

  Fly    84 LVDMSRVQDEEVGDGTTSVTVLASELLREAEKLVEQKLHPQIIVSGWRQATQVALEALTAAAQDN 148
            :.|::...:||.|||||:.||||..:.:|..:.:.:..:|..|    |:...:|::|:.|..:..
Mouse    98 VQDVANNTNEEAGDGTTTATVLARSIAKEGFEKISKGANPVEI----RRGVMLAVDAVIAELKKQ 158

  Fly   149 S---SSDEKFRNDLLNIARTTLSSKILHQHKDFFANLAVDAVMRLKGSGELKSIQIIKKSGGTLG 210
            |   ::.|    ::..:|  |:|:   :..|| ..|:..||:.::...|     .|..|.|.||.
Mouse   159 SKPVTTPE----EIAQVA--TISA---NGDKD-IGNIISDAMKKVGRKG-----VITVKDGKTLN 208

  Fly   211 DSF-LDEGFLLDKKPGVHQPQRIENARILIANTPMDTDKIKVFGSSIKVDSLAKIAD-LEMAEKE 273
            |.. :.||...|:  |...|..|..::    ....:.....|..|..|:.|:..|.. ||:|...
Mouse   209 DELEIIEGMKFDR--GYISPYFINTSK----GQKCEFQDAYVLLSEKKISSVQSIVPALEIANAH 267

  Fly   274 K-----MKEKVDKILKHKCNVFINRQLIYNYPEQLFADARVMSIEHADF-----DGIERLAYCTG 328
            :     :.|.||.  :....:.:||         |....:|::::...|     :.::.:|..||
Mouse   268 RKPLVIIAEDVDG--EALSTLVLNR---------LKVGLQVVAVKAPGFGDNRKNQLKDMAIATG 321

  Fly   329 ------------------------GEIVSTFENPSLVKLGECD----------VIEQVMIG---- 355
                                    ||::.|.::..|:| |:.|          :.||:.|.
Mouse   322 GAVFGEEGLNLNLEDVQAHDLGKVGEVIVTKDDAMLLK-GKGDKAHIEKRIQEITEQLDITTSEY 385

  Fly   356 EDTLLRFSGVKLGEACTIVIRGATQQI-LDEADRSLHDALCVLAATVKESRIIFGGGCS--EALM 417
            |...|.....||.:...::..|.|..: ::|....:.|||....|.|:|. |:.||||:  ..:.
Mouse   386 EKEKLNERLAKLSDGVAVLKVGGTSDVEVNEKKDRVTDALNATRAAVEEG-IVLGGGCALLRCIP 449

  Fly   418 ATAVLKKAAETPGKEAIAIEAFARALLSLPTAIADNAGYDSAQLVSELRAGHAQGKQTLGLDMEL 482
            |...||.|.|   .:.|.||...|||......||.|||.:.:.:|.::    .|....:|.|..|
Mouse   450 ALDSLKPANE---DQKIGIEIIKRALKIPAMTIAKNAGVEGSLIVEKI----LQSSSEVGYDAML 507

  Fly   483 GKVADVRELGITESFAVKRQVLMSASEAAEMILRVDNIIRCAPR 526
            |...::.|.||.:...|.|..|:.|:..|.::...:.::...|:
Mouse   508 GDFVNMVEKGIIDPTKVVRTALLDAAGVASLLTTAEAVVTEIPK 551

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCT2	NP_572524.1	TCP1_beta	10..527	CDD:239452	140/564 (25%)
Hspd1	NP_034607.3	GroEL	28..548	CDD:239460	139/559 (25%)