Protein Alignment CCT2 and CCT8

DIOPT Version :10

• Sequence 1: NP_572524.1
• Gene: CCT2 / 31838
• FlyBaseID: FBgn0030086
• Length: 535
• Species: Drosophila melanogaster
• Sequence 2: XP_314553.3
• Gene: CCT8 / 1275315
• VectorBaseID: AGAMI1_001421
• Length: 546
• Species: Anopheles gambiae
• Alignment Length: 523
• Identity: 148/523 - (28%)
• Similarity: 253/523 - (48%)
• Gaps: 51/523 - (9%)

  Fly    38 VKSTLGPKGMDKILVATGRNAGHVE---VTNDGATILRAVGVDNPAAKILVDMSRVQDEEVGDGT 99
            |:|..||.||:|:::      .|:|   ||:|..||:|.:.|::||||::::.|::|:.|.||||
Mosquito    43 VRSAYGPNGMNKMII------NHIEKQFVTSDAGTIMRELDVEHPAAKLMIEASQMQEAEAGDGT 101

  Fly   100 TSVTVLASELLREAEKLVEQKLHPQIIVSGWRQATQVALEALTAAAQDNSSSDEKFRNDLLNIAR 164
            ..|.|....||.|||:|:...:....|..|:.:|.|..|:.|...: .:...|.:....:.|..|
Mosquito   102 NFVVVFCGALLEEAEELLRLGVTSSDITEGYEKALQKTLDILPTLS-CHEIKDYRSLVPVRNAIR 165

  Fly   165 TTLSSKILHQHKDFFANLAVDA---VMRLKGSGELKSIQIIKKSGGTLGDSFLDEGFLLDKKPGV 226
            .|:.||.| .::||.|:|...|   :|..|.:..:.:|::.|..|..|..|        :..||:
Mosquito   166 ATVMSKQL-GNEDFLADLIAKACISIMPEKTTFNVDNIRVCKILGSGLQMS--------EVIPGM 221

  Fly   227 HQPQRIE-------NARILIANTPMDTDKIKVFGSSIKVDSLAKIADLEMAEKEKMKEKVDKILK 284
            ...:.:|       .|:|.:.:.|:|..:.:..| ::.:.|..::......|:..::.::..|:.
Mosquito   222 VFKRFVEGEVTSATKAKIALYSCPVDIIQTETKG-TVLIKSADELKTFSQGEENLLEAQIKAIVD 285

  Fly   285 HKCNVFI------NRQLIYNYPEQLFADARVMSIEHADFDGIERLAYCTGGEIVSTFENPSLVKL 343
            ....|.:      :..|.|.....|.| .|:    ::.|| :.||:...||.::.....||..:|
Mosquito   286 TGATVIVAGAKFGDMALHYMNKYGLMA-VRL----NSKFD-LRRLSKAVGGTVLPRLTPPSTEEL 344

  Fly   344 GECDVIEQVMIGED--TLLRFSGVKLGEACTIVIRGATQQILDEADRSLHDALCVLAATVKESRI 406
            |.||.:....:|:.  |:.:..|.: ....|:||||:|...:|:.:|.:.|.:.......::.|.
Mosquito   345 GYCDNVYLHELGDTSVTIFKSEGTE-SRIATVVIRGSTDNYMDDIERVIDDGVNTFKGLTRDGRF 408

  Fly   407 IFGGGCSEALMATAVLKKAAETPGKEAIAIEAFARALLSLPTAIADNAGYDSAQLVSELRAGHAQ 471
            :.|.|..|..:|..:.:.|...||.|..|:..||:||...|.|:|:|:|.::.::|.:|...|.|
Mosquito   409 LPGAGAVEIELAQQLAEYADTLPGLEQYAVRKFAKALEYFPKALAENSGVNATEVVHQLYLAHKQ 473

  Fly   472 GKQTLGLDMELGKVA--DVRELGITESFAVKRQVLMSASEAAEMILRVDNIIRC----APRRRVP 530
            ||:|.|.|:|..:.|  ||....|.:.:..|...|..|..||..||:||.||..    .|:.|..
Mosquito   474 GKKTEGFDIESEQPATIDVTTKNIFDLYTTKYWGLKYAVGAACTILKVDEIIMAKRAGGPKPRAG 538

  Fly   531 DRG 533
            ..|
Mosquito   539 GPG 541

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCT2	NP_572524.1	TCP1_beta	10..527	CDD:239452	146/515 (28%)
CCT8	XP_314553.3	chaperonin_like	10..538	CDD:351886	147/518 (28%)