Protein Alignment CCT2 and CCT1

DIOPT Version :10

• Sequence 1: NP_572524.1
• Gene: CCT2 / 31838
• FlyBaseID: FBgn0030086
• Length: 535
• Species: Drosophila melanogaster
• Sequence 2: XP_313154.4
• Gene: CCT1 / 1274083
• VectorBaseID: AGAMI1_012504
• Length: 557
• Species: Anopheles gambiae
• Alignment Length: 534
• Identity: 187/534 - (35%)
• Similarity: 300/534 - (56%)
• Gaps: 42/534 - (7%)

  Fly    24 RLSSFIGAIAIGDLVKSTLGPKGMDKILVATGRNAGHVEVTNDGATILRAVGVDNPAAKILVDMS 88
            |..:.:.|.:|.::|||:|||.|:||:||   .:.|.|.|||||||||:.:.|::||||:|.:::
Mosquito    21 RTQNVMAASSIANIVKSSLGPVGLDKMLV---DDIGDVTVTNDGATILKLLEVEHPAAKVLCELA 82

  Fly    89 RVQDEEVGDGTTSVTVLASELLREAEKLVEQKLHPQIIVSGWRQATQVAL----EALTAAAQDNS 149
            ::||||||||||||.::|:|||:.|::||:||:||..|::|:|.|.:.|.    |.|||..
Mosquito    83 QLQDEEVGDGTTSVVIIAAELLKNADELVKQKIHPTSIIAGYRLACKEACKYISEHLTAPV---- 143

  Fly   150 SSDEKFRNDLLNIARTTLSSKILHQHKDFFANLAVDAVMRLK-------GSGELKSIQIIKKSGG 207
              |:..|..|:|:|:|::||||:....||||.:.|||...:|       .:..:|::.::|..|.
Mosquito   144 --DDLGRETLINVAKTSMSSKIIGADADFFATMVVDAAQAVKILDPKGNPAYPIKAVNVLKAHGK 206

  Fly   208 TLGDSFLDEGFLLDKKPGVHQ-PQRIENARILIANTPMDTDKIKVFGSSIKVDSLAKIADLEMAE 271
            :..:|.|.:|:.|:......| |::|.||:|...:..:...|:|: |..:.:....|:..:...|
Mosquito   207 SARESILVQGYALNCTIASQQMPKKIVNAKIACLDFSLQKTKMKM-GVQVLITDPEKLEGIRARE 270

  Fly   272 KEKMKEKVDKILKHKCNVFINRQLIYNYPEQLFADARVMSIEHADFDGIERLAYCTGGEIVSTFE 336
            .:..|||::|||....||.:....|.:...:.|.:|..|::.......::|:|..||...:::..
Mosquito   271 LDITKEKIEKILATGVNVVLCSGGIDDLCLKYFVEAGAMAVRRVKKADLKRIAKATGAAYLTSLT 335

  Fly   337 N--------PSLVKLGECDVIEQVMIGEDTLLRFSGVKLGEACTIVIRGATQQILDEADRSLHDA 393
            |        .|.|  ||...:.|..|.:|.|:...|.|...|.:|::||......||.:||:|||
Mosquito   336 NMEGEESFDASYV--GEAAEVVQEFICDDELILIRGPKARTAASIILRGPNDFYCDEMERSIHDA 398

  Fly   394 LCVLAATVKESRIIFGGGCSEALMATAVLKKAAETPGKEAIAIEAFARALLSLPTAIADNAGYDS 458
            |||....::..:::.||||.||.::..:...|.....:|.:||..||::||.:|..:|.||..|:
Mosquito   399 LCVAKRVLEGKKVVAGGGCVEAALSIYLENFATSLSSREQLAIAEFAKSLLVIPKTLAVNAAKDA 463

  Fly   459 AQLVSELRAGHAQGKQTL---------GLDMELGKVADVRELGITESFAVKRQVLMSASEAAEMI 514
            ..||::|||.| ...||:         |||:..|.|.|.::.|:.|....|.:.|..|:|||..|
Mosquito   464 TDLVAKLRAYH-NSSQTVVDHAQLKWYGLDLIEGVVKDNKKAGVLEPAMSKIKSLKFATEAAITI 527

  Fly   515 LRVDNIIRCAPRRR 528
            ||:|::|...|..:
Mosquito   528 LRIDDMITLNPEEK 541

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCT2	NP_572524.1	TCP1_beta	10..527	CDD:239452	187/531 (35%)
CCT1	XP_313154.4	TCP1_alpha	12..538	CDD:239451	186/529 (35%)