Protein Alignment CCT2 and Cct8

DIOPT Version :10

• Sequence 1: NP_572524.1
• Gene: CCT2 / 31838
• FlyBaseID: FBgn0030086
• Length: 535
• Species: Drosophila melanogaster
• Sequence 2: NP_033970.3
• Gene: Cct8 / 12469
• MGIID: 107183
• Length: 548
• Species: Mus musculus
• Alignment Length: 503
• Identity: 135/503 - (26%)
• Similarity: 252/503 - (50%)
• Gaps: 23/503 - (4%)

  Fly    34 IGDLVKSTLGPKGMDKILVATGRNAGHVEVTNDGATILRAVGVDNPAAKILVDMSRVQDEEVGDG 98
            :....::..||.||:|:::   .....:.||||.|||||.:.|.:||||::|..|.:|::|||||
Mouse    39 LAQTTRTAYGPNGMNKMVI---NRLEKLFVTNDAATILRELEVQHPAAKMIVMASHMQEQEVGDG 100

  Fly    99 TTSVTVLASELLREAEKLVEQKLHPQIIVSGW----RQATQVALEALTAAAQDNSSSDEKFRNDL 159
            |..|.|.|..||..||:|:...|....::||:    ::|.::..|.:..:|::....||     :
Mouse   101 TNFVLVFAGALLELAEELLRIGLSVSEVISGYEIACKKAHEILPELVCCSAKNLRDVDE-----V 160

  Fly   160 LNIARTTLSSKILHQHKDFFANLAVDAVMRL---KGSGELKSIQIIKKSGGTLGDSFLDEGFLLD 221
            .::.||::.|| .:..:.|.|.|...|.:.:   .|:..:.:|::.|..|..:..|.:..|.:.
Mouse   161 SSLLRTSIMSK-QYGSETFLAKLIAQACVSIFPDSGNFNVDNIRVCKILGSGIYSSSVLHGMVF- 223

  Fly   222 KKPGVHQPQRIENARILIANTPMDTDKIKVFGSSIKVDSLAKIADLEMAEKEKMKEKVDKILKHK 286
            ||........:::|:|.:.:.|.| ..|.....::.:.:..::.:....|:..|..:|..|....
Mouse   224 KKETEGDVTSVKDAKIAVYSCPFD-GMITETKGTVLIKTAEELMNFSKGEENLMDAQVKAIAGTG 287

  Fly   287 CNVFINRQLIYNYPEQLFADARVMSIE-HADFDGIERLAYCTGGEIVSTFENPSLVKLGECDVIE 350
            .||.:....:.:..........:|.:. ::.:| :.||....|...:.....|...::|.||.:.
Mouse   288 ANVIVTGGKVADIALHYANKYNIMLVRLNSKWD-LRRLCKTVGATALPKLTPPVQEEMGHCDSVY 351

  Fly   351 QVMIGEDTLLRFSGVKL-GEACTIVIRGATQQILDEADRSLHDALCVLAATVKESRIIFGGGCSE 414
            ...:|:..::.|...|. |...|||:||:|..::|:.:|::.|.:.......::.|::.|||.:|
Mouse   352 LSEVGDTQVVVFKHEKEDGAISTIVLRGSTDNLMDDIERAVDDGVNTFKVLTRDKRLVPGGGATE 416

  Fly   415 ALMATAVLKKAAETPGKEAIAIEAFARALLSLPTAIADNAGYDSAQLVSELRAGHAQGKQTLGLD 479
            ..:|..:.......||.|..||:.||.|..::|.|:|:|:|..:.:::|:|.:.|.:|.:.:|||
Mouse   417 IELAKQITSYGETCPGLEQYAIKKFAEAFEAIPRALAENSGVKANEVISKLYSVHQEGNKNVGLD 481

  Fly   480 M--ELGKVADVRELGITESFAVKRQVLMSASEAAEMILRVDNIIRCAP 525
            :  |:..|.|:.|..|.:::..|...:..|:.||..:||||.||...|
Mouse   482 IEAEVPAVKDMLEASILDTYLGKYWAIKLATNAAVTVLRVDQIIMAKP 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCT2	NP_572524.1	TCP1_beta	10..527	CDD:239452	135/503 (27%)
Cct8	NP_033970.3	chap_CCT_theta	10..539	CDD:274087	135/503 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	529..548		1/1 (100%)