Protein Alignment CCT2 and Cct6b

DIOPT Version :10

• Sequence 1: NP_572524.1
• Gene: CCT2 / 31838
• FlyBaseID: FBgn0030086
• Length: 535
• Species: Drosophila melanogaster
• Sequence 2: NP_033969.2
• Gene: Cct6b / 12467
• MGIID: 1329013
• Length: 531
• Species: Mus musculus
• Alignment Length: 536
• Identity: 150/536 - (27%)
• Similarity: 279/536 - (52%)
• Gaps: 37/536 - (6%)

  Fly     8 VRVLKNEAQEEKAEMARLSSFIGAIAIGDLVKSTLGPKGMDKILVATGRNAGHVEVTNDGATILR 72
            :::....|:..:::.|...:...|..:.|:::.||||||..|:||:   .||.:::|.||..:|.
Mouse     4 IKIANPGAEVTRSQAALAVNICAARGLQDVLRPTLGPKGALKMLVS---GAGDIKLTKDGNVLLH 65

  Fly    73 AVGVDNPAAKILVDMSRVQDEEVGDGTTSVTVLASELLREAEKLVEQKLHPQIIVSGWRQATQVA 137
            .:.:.:|.|.|:..::..||...||||||..::..|||::|:..:.:.|||:||..|:..|...|
Mouse    66 EMQIQHPTASIIAKVAAAQDHVTGDGTTSNVLIIGELLKQADLYISEGLHPRIITEGFDVAKTKA 130

  Fly   138 LEALTAAAQDNSSSDEKFRNDLLNIARTTLSSKILHQHKDFFANLAVDAVMRLKGSG---ELKSI 199
            ||.|    .:.....|..|..||::|||:|.:|:..:..|......||:|:.::..|   :|..:
Mouse   131 LEVL----DEIKVQKEMKREILLDVARTSLQTKVHAELADILTEAVVDSVLAIRRPGVPIDLFMV 191

  Fly   200 QIIKKSGGTLGDSFLDEGFLLDKKPGVHQP---QRIENARILIANTPMDTDKIKVFGSSIKVDSL 261
            :|::....:..|:.|..|.:||.  |...|   :::.:|.||..|..::.:|.:| .|.....::
Mouse   192 EIVEMRHKSETDTQLIRGLVLDH--GARHPRMRKQVRDAYILTCNVSLEYEKTEV-SSGFFYKTV 253

  Fly   262 AKIADLEMAEKEKMKEKVDKIL---------KHKCNVFINRQLIYNYPEQLFADARVMSIEHADF 317
            .:...|..||::.::::|.||:         .:|..|.||::.|.....::.|...::::..|..
Mouse   254 EEKEKLVKAERKFIEDRVQKIIDLKQKVCAESNKGFVVINQKGIDPVSLEMLAKHNIVALRRAKR 318

  Fly   318 DGIERLAYCTGGEIVSTFENPSLVKLGECDVIEQVMIGEDTLLRFSGVKLGEAC------TIVIR 376
            ..:|||....||..|::||..|...||...::.:..:||:   :|:.:   |.|      |::::
Mouse   319 RNLERLTLACGGLAVNSFEGLSEECLGHAGLVFEYALGEE---KFTFI---EDCVNPLSVTLLVK 377

  Fly   377 GATQQILDEADRSLHDALCVLAATVKESRIIFGGGCSEALMATAVLKKAAETPGKEAIAIEAFAR 441
            |..:..|.:...:|.|.|..:...:::..::.|.|..|..:|.|::.......|:..:.|:|||.
Mouse   378 GPNKHTLIQIKDALRDGLRAVKNAIEDGCVVPGAGAVEVAIAEALVNYKHRVQGRVRLGIQAFAD 442

  Fly   442 ALLSLPTAIADNAGYDSAQLVSELRAGHAQGKQTLGLDMELGKVADVRELGITESFAVKRQVLMS 506
            |||.:|..:|.|:|||..:.:.:::..||:.|:.||:|:..|:.....|.||.:::.||:.:|.|
Mouse   443 ALLIIPKVLAQNSGYDLQETLIKIQTKHAESKELLGIDLNTGEPMAAAEAGIWDNYCVKKHLLHS 507

  Fly   507 ASEAAEMILRVDNIIR 522
            .:..|..||.||.|:|
Mouse   508 CTVIATNILLVDEIMR 523

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCT2	NP_572524.1	TCP1_beta	10..527	CDD:239452	150/534 (28%)
Cct6b	NP_033969.2	chap_CCT_zeta	3..530	CDD:274088	150/536 (28%)