Protein Alignment CCT2 and Cct5

DIOPT Version :10

• Sequence 1: NP_572524.1
• Gene: CCT2 / 31838
• FlyBaseID: FBgn0030086
• Length: 535
• Species: Drosophila melanogaster
• Sequence 2: NP_031663.1
• Gene: Cct5 / 12465
• MGIID: 107185
• Length: 541
• Species: Mus musculus
• Alignment Length: 526
• Identity: 174/526 - (33%)
• Similarity: 294/526 - (55%)
• Gaps: 19/526 - (3%)

  Fly     7 PVRVLKNEAQEEKAEMARL----SSFIGAIAIGDLVKSTLGPKGMDKILVATGRNAGHVEVTNDG 67
            |..::|:  |:.|:.:..|    |..:.|.|:.:.::::|||.|:||::|   ...|.|.:||||
Mouse    15 PFLIIKD--QDRKSRLMGLEALKSHIMAAKAVANTMRTSLGPNGLDKMMV---DKDGDVTITNDG 74

  Fly    68 ATILRAVGVDNPAAKILVDMSRVQDEEVGDGTTSVTVLASELLREAEKLVEQKLHPQIIVSGWRQ 132
            ||||..:.||:..||::|::|:.||:|:|||||.|.|||..||.|||:|:::.:||..|..|:.|
Mouse    75 ATILSMMDVDHQIAKLMVELSKSQDDEIGDGTTGVVVLAGALLEEAEQLLDRGIHPIRIADGYEQ 139

  Fly   133 ATQVALEALTAAAQDNSSSDEKFRNDLLNIARTTLSSKILHQHKDFFANLAVDAVMRL----KGS 193
            |.::|::.|...: |....|......|:..|:|||.||:::......|.:||:||:.:    :..
Mouse   140 AARIAIQHLDKIS-DKVLVDINNPEPLIQTAKTTLGSKVINSCHRQMAEIAVNAVLTVADMERRD 203

  Fly   194 GELKSIQIIKKSGGTLGDSFLDEGFLLDKKPGVHQ-PQRIENARILIANTPMDTDKIKVFGSSIK 257
            .:.:.|::..|.||.|.|:.|.:|.::||.....| |:::.:|:|.|...|.:..|.|. ...:.
Mouse   204 VDFELIKVEGKVGGRLEDTKLIKGVIVDKDFSHPQMPKKVVDAKIAILTCPFEPPKPKT-KHKLD 267

  Fly   258 VDSLAKIADLEMAEKEKMKEKVDKILKHKCNVFINRQLIYNYPEQLFADARVMSIEHADFDGIER 322
            |.|:.....|:..||||.:|.:.:|.:...|:.|.:....:....|.....:.::.......||.
Mouse   268 VMSVEDYKALQKYEKEKFEEMIKQIKETGANLAICQWGFDDEANHLLLQNGLPAVRWVGGPEIEL 332

  Fly   323 LAYCTGGEIVSTFENPSLVKLGECDVIEQVMIG--EDTLLRFSGVKLGEACTIVIRGATQQILDE 385
            :|..|||.||..|...:..|||...|::::..|  :|.:|.....|...|.||.|||..:.|::|
Mouse   333 IAIATGGRIVPRFSELTSEKLGFAGVVQEISFGTTKDKMLVIEKCKNSRAVTIFIRGGNKMIIEE 397

  Fly   386 ADRSLHDALCVLAATVKESRIIFGGGCSEALMATAVLKKAAETPGKEAIAIEAFARALLSLPTAI 450
            |.|||||||||:...::::|:::|||.:|...|.||.::|.:.|..|..|:.|||.||..:|.|:
Mouse   398 AKRSLHDALCVIRNLIRDNRVVYGGGAAEISCALAVSQEADKCPTLEQYAMRAFADALEVIPMAL 462

  Fly   451 ADNAGYDSAQLVSELRAGHA-QGKQTLGLDMELGKVADVRELGITESFAVKRQVLMSASEAAEMI 514
            ::|:|.:..|.::|:||... :....||:|.......|::...:.|:...|:|.:..|::...||
Mouse   463 SENSGMNPIQTMTEVRARQVKESNPALGIDCLHKGSNDMQYQHVIETLIGKKQQISLATQMVRMI 527

  Fly   515 LRVDNI 520
            |::|:|
Mouse   528 LKIDDI 533

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCT2	NP_572524.1	TCP1_beta	10..527	CDD:239452	173/523 (33%)
Cct5	NP_031663.1	TCP1_epsilon	10..535	CDD:239455	174/526 (33%)