DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CCT2 and hspd1

DIOPT Version :9

Sequence 1:	NP_572524.1	Gene:	CCT2 / 31838	FlyBaseID:	FBgn0030086	Length:	535	Species:	Drosophila melanogaster
Sequence 2:	NP_001096355.1	Gene:	hspd1 / 100124945	XenbaseID:	XB-GENE-980059	Length:	576	Species:	Xenopus tropicalis

Alignment Length:	564	Identity:	133/564 - (23%)
Similarity:	226/564 - (40%)	Gaps:	108/564 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 ARLSSFIGAIAIGDLVKSTLGPKGMDKILVATGRNAGHVEVTNDGATILRAVGV----DNPAAKI 83
            ||.....|...:.|.|..|:||||...|:   .::.|..:||.||.|:.:|:.:    .|..||:
Frog    36 ARALMLQGVDLLADAVAVTMGPKGRTVII---EQSWGSPKVTKDGVTVAKAIDLKDKYKNIGAKL 97

  Fly    84 LVDMSRVQDEEVGDGTTSVTVLASELLREAEKLVEQKLHPQIIVSGWRQATQVALEALTAAAQDN 148
            :.|::...:||.|||||:.||||..:.:|..:.:.:..:|..|..|...|....::.|...::..
Frog    98 VQDVANNTNEEAGDGTTTATVLARSIAKEGFEKISKGANPVEIRRGVMMAVDAVIKELKNQSKPV 162

  Fly   149 SSSDEKFRNDLLNIARTTLSSKILHQHKDFFANLAVDAVMRLKGSGELKSIQIIKKSGGTLGDSF 213
            ::.:|        ||:....|....|.   ...:..||:.|:...|     .|..|.|.||.|..
Frog   163 TTPEE--------IAQVATISANGDQE---IGKIISDAMKRVGRRG-----VITVKDGKTLHDEL 211

  Fly   214 -LDEGFLLDKKPGVHQPQRIENARILIANTPMDTDKIKVFGSSIKVDSLAKIAD-LEMAEKEK-- 274
             :.||...|:  |...|..|..|:    ....:.....:..|..|:.|:..|.. ||:|...:
Frog   212 EIIEGMKFDR--GYISPYFINTAK----GQKCEFQDAYLLLSEKKISSVQSIVPALEIANAHRKP 270

  Fly   275 ---MKEKVDKILKHKCNVFINRQLIYNYPEQLFADARVMSIEHADF-----DGIERLAYCTG--- 328
               :.|.||.  :....:.:||         |....:|::::...|     :.::.:|..:|
Frog   271 LVIIAEDVDG--EALSTLVLNR---------LKVGLQVVAVKAPGFGDNRKNQLKDMAISSGGVV 324

  Fly   329 ---------------------GEIVSTFENPSLVKLGECD----------VIEQVMIGEDTLLRF 362
                                 ||::.|.::..|:| |:.|          :.||:   |.|...:
Frog   325 FGEEGLTLNIEDIQPHDFGKVGEVIVTKDDTMLLK-GKGDKAQIEKRIQEIHEQL---ESTNSEY 385

  Fly   363 SGVKLGE--------ACTIVIRGATQQILDEADRSLHDALCVLAATVKESRIIFGGGCS--EALM 417
            ...||.|        ...|.:.|.:...::|....:.|||....|.|:|. |:.||||:  ..:.
Frog   386 EKEKLNERLAKLSDGVAVIKVGGTSDVEVNEKKDRVTDALNATRAAVEEG-IVLGGGCALLRCIP 449

  Fly   418 ATAVLKKAAETPGKEAIAIEAFARALLSLPTAIADNAGYDSAQLVSELRAGHAQGKQTLGLDMEL 482
            |...|..|.|   .:.:.||...|.|......||.|||.:.:.:|.::    .|....:|.|...
Frog   450 ALEALNPANE---DQRVGIEIIRRTLKIPAMTIAKNAGVEGSLVVEKI----IQSPVEIGYDAMH 507

  Fly   483 GKVADVRELGITESFAVKRQVLMSASEAAEMILRVDNIIRCAPR 526
            .:..::.|.||.:...|.|..||.|:..|.::...:.::...|:
Frog   508 AEFVNLVEKGIIDPTKVVRTALMDAAGVASLLTTAEAVVTEIPK 551

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CCT2	NP_572524.1	PTZ00212	1..530	CDD:185514	133/564 (24%)
CCT2	NP_572524.1	TCP1_beta	10..527	CDD:239452	133/564 (24%)
hspd1	NP_001096355.1	GroEL	28..548	CDD:239460	132/559 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910