Protein Alignment HP1b and CBX2

DIOPT Version :9

• Sequence 1: NP_001162713.1
• Gene: HP1b / 31834
• FlyBaseID: FBgn0030082
• Length: 240
• Species: Drosophila melanogaster
• Sequence 2: XP_011523684.1
• Gene: CBX2 / 84733
• HGNCID: 1552
• Length: 586
• Species: Homo sapiens
• Alignment Length: 361
• Identity: 80/361 - (22%)
• Similarity: 113/361 - (31%)
• Gaps: 134/361 - (37%)

  Fly     4 FSVERVEDKRTVNGRTEYYLKWKGYPRSENTWEPVENLDCPDLIANF-----EESLKNNKKETK- 62
            |:.|.:..||...|:.||.:||:|:....|:|||.||:..|.|:..|     |:.::|.|:..:
Human    12 FAAECILSKRLRKGKLEYLVKWRGWSSKHNSWEPEENILDPRLLLAFQKKEHEKEVQNRKRGKRP 76

  Fly    63 --------------------------KRLSTSSTPESIRSKRKSFLEDDTE-------------- 87
                                      |..|:||:..|..|...|..|||::
Human    77 RGRPRKLTAMSSCSRRSKLKEPDAPSKSKSSSSSSSSTSSSSSSDEEDDSDLDAKRGPRGRETHP 141

  Fly    88 -------------EQKKLIGFERGLE---------------------ASKILGATDS------SG 112
                         |.|..|..:||.:                     |.|.|||..|      |.
Human   142 VPQKKAQILVAKPELKDPIRKKRGRKPLPPEQKATRRPVSLAKVLKTARKDLGAPASKLPPPLSA 206

  Fly   113 HLMFLMKWK-------GSDHADLVPAKLAN-----TRCP-------QVVIQFYEERLTWHTGSGN 158
            .:..|...|       |...|...|..||:     ...|       |..|..|..|:|.......
Human   207 PVAGLAALKAHAKEACGGPSAMATPENLASLMKGMASSPGRGGISWQSSIVHYMNRMTQSQAQAA 271

  Fly   159 GN-----GNTNSVNLG-------SSGGLGSVGGSGAGDDTAPG------SVGTTGGGSNIDGGDE 205
            ..     ..||...||       ..|.|| :...|:....||.      .||.|||..:..|...
Human   272 SRLALKAQATNKCGLGLDLKVRTQKGELG-MSPPGSKIPKAPSGGAVEQKVGNTGGPPHTHGASR 335

  Fly   206 -----EDPEPASPIGSINQDENIKPDESSELDNGQP 236
                 ..|:||.     .|:.:::..:...:.||.|
Human   336 VPAGCPGPQPAP-----TQELSLQVLDLQSVKNGMP 366

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HP1b	NP_001162713.1	CHROMO	3..52	CDD:214605	19/52 (37%)
		Chromo_shadow	100..151	CDD:279701	19/96 (20%)
CBX2	XP_011523684.1	Chromo	15..61	CDD:278797	18/45 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1628171at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920