DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment HP1b and cbx3a

DIOPT Version :9

Sequence 1:	NP_001162713.1	Gene:	HP1b / 31834	FlyBaseID:	FBgn0030082	Length:	240	Species:	Drosophila melanogaster
Sequence 2:	XP_005173826.1	Gene:	cbx3a / 751689	ZFINID:	ZDB-GENE-030131-1158	Length:	177	Species:	Danio rerio

Alignment Length:	156	Identity:	93/156 - (59%)
Similarity:	113/156 - (72%)	Gaps:	10/156 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 EFSVERVEDKRTVNGRTEYYLKWKGYPRSENTWEPVENLDCPDLIANFEESLKN--NKKETKKRL 65
            ||.||:|.|:|.|||:.|::|||||:..::|||||.||||||:|||.|.||.|.  .|.|..||.
Zfish    21 EFVVEKVMDQRVVNGKVEFFLKWKGFTDADNTWEPEENLDCPELIAAFLESQKGVVEKPEAVKRK 85

  Fly    66 STSSTPES--IRSKRKSFLEDDTEEQKKLIGFERGLEASKILGATDSSGHLMFLMKWKGSDHADL 128
            |::..||:  .::|||..:.|      |..||.|.||..:|:|||||||.||||||||.||.|||
Zfish    86 SSTDEPETEESKAKRKKEMSD------KPRGFARNLEPERIIGATDSSGELMFLMKWKDSDEADL 144

  Fly   129 VPAKLANTRCPQVVIQFYEERLTWHT 154
            |||:.|||||||:||.|||||||||:
Zfish   145 VPAREANTRCPQIVIAFYEERLTWHS 170

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
HP1b	NP_001162713.1	CHROMO	3..52	CDD:214605	31/48 (65%)
HP1b	NP_001162713.1	Chromo_shadow	100..151	CDD:279701	39/50 (78%)
cbx3a	XP_005173826.1	Chromo	23..71	CDD:278797	29/47 (62%)
cbx3a	XP_005173826.1	Chromo_shadow	116..167	CDD:279701	39/50 (78%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170575834
Domainoid	1	1.000	91	1.000	Domainoid score	I7663
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	183	1.000	Inparanoid score	I3949
OMA	1	1.010	-	-		QHG52905
OrthoDB	1	1.010	-	-		D1628171at2759
OrthoFinder	1	1.000	-	-		FOG0000191
OrthoInspector	1	1.000	-	-		otm25057
orthoMCL	1	0.900	-	-		OOG6_104220
Panther	1	1.100	-	-	LDO	PTHR22812
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R8954
SonicParanoid	1	1.000	-	-		X422
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	14	13.940