DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment HP1b and cdyl

DIOPT Version :9

Sequence 1:	NP_001162713.1	Gene:	HP1b / 31834	FlyBaseID:	FBgn0030082	Length:	240	Species:	Drosophila melanogaster
Sequence 2:	XP_696879.5	Gene:	cdyl / 568457	ZFINID:	ZDB-GENE-070912-561	Length:	581	Species:	Danio rerio

Alignment Length:	294	Identity:	59/294 - (20%)
Similarity:	93/294 - (31%)	Gaps:	109/294 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 FSVERVEDKR-TVNGRTEYYLKWKGYPRSENTWEPVENL-DCPDLIANFEESLKNNKKETKKRLS 66
            :.|||:..|| ...|:|||.::|:||....:||||..:| .|.:.|..|.......:|:.....|
Zfish     8 YEVERIIGKRKNKKGKTEYLVRWRGYSFEGDTWEPEGHLSSCIEFIHEFNRQHSEKQKDGTLLRS 72

  Fly    67 TSSTPE----SIRSKRK----------------------------------SFLEDDTEEQKKLI 93
            |.|:|.    ||.::::                                  |..:.|:.:||:
Zfish    73 TRSSPSTANTSINARKQISRPQHPSANSNTAKTSTPTPNTHPTKRPQPAQNSSNDSDSPQQKR-- 135

  Fly    94 GFERGLEASKILGAT------------------------DSSGHLMFLMK--------------- 119
              .|....|.|:|..                        ..||..:.:.|
Zfish   136 --GRSAGTSSIMGTVTETAPTAAPAAAPTVSALRRSMDLSKSGIKILVPKSPMNSRADTEESPSE 198

  Fly   120 -----WKGSDHADLVPAKLANTRCPQVVIQF-YEERLTWHT--------------------GSGN 158
                 .:||...|.||.::|....|...::. .|||....|                    .:.|
Zfish   199 AAHSLEQGSQEPDAVPPEVALLEKPAGAMRVPGEERARMGTRPRTQTALPPPQIPITPAAVRTLN 263

  Fly   159 GNGNTNSVNLGSSGGLGSVGGSGAGDDTAPGSVG 192
            |.|.|..:...|:.|......:.||..::.|..|
Zfish   264 GKGVTTLMEASSANGTAITQSAAAGVMSSSGLTG 297

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
HP1b	NP_001162713.1	CHROMO	3..52	CDD:214605	20/49 (41%)
HP1b	NP_001162713.1	Chromo_shadow	100..151	CDD:279701	16/95 (17%)
cdyl	XP_696879.5	CHROMO	8..61	CDD:214605	20/52 (38%)
cdyl	XP_696879.5	crotonase-like	327..523	CDD:119339
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1911
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810