DRSC/TRiP Functional Genomics Resources

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Protein Alignment HP1b and MPHOSPH8

DIOPT Version :10

Sequence 1:NP_572521.2 Gene:HP1b / 31834 FlyBaseID:FBgn0030082 Length:240 Species:Drosophila melanogaster
Sequence 2:XP_047286351.1 Gene:MPHOSPH8 / 54737 HGNCID:29810 Length:879 Species:Homo sapiens


Alignment Length:95 Identity:31/95 - (32%)
Similarity:52/95 - (54%) Gaps:7/95 - (7%)


- Green bases have known domain annotations that are detailed below.


  Fly     4 FSVERVEDKRTVNGRTEYYLKWKGYPRSENTWEPVENL-DCPDLIANFEESLKNNK-KETKKRLS 66
            |.||::.|.:|..|:..|.::||||...::||||..:| ||.:::..|.:.:..|| |..:|.:.
Human    59 FEVEKILDMKTEGGKVLYKVRWKGYTSDDDTWEPEIHLEDCKEVLLEFRKKIAENKAKAVRKDIQ 123

  Fly    67 TSSTPESI-----RSKRKSFLEDDTEEQKK 91
            ..|....|     .|.::|..::||..:||
Human   124 RLSLNNDIFEANSDSDQQSETKEDTSPKKK 153

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
HP1bNP_572521.2 CD_HP1_like 3..52 CDD:349281 19/48 (40%)
CSD 99..150 CDD:349275
MPHOSPH8XP_047286351.1 CD_MMP8 58..108 CDD:349283 19/48 (40%)
PTZ00121 <200..>550 CDD:173412
ANKYR 485..746 CDD:440430
ANK repeat 600..631 CDD:293786
ANK repeat 633..664 CDD:293786
ANK repeat 666..695 CDD:293786
Blue background indicates that the domain is not in the aligned region.

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