DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment HP1b and cbx1b

DIOPT Version :9

Sequence 1:	NP_001162713.1	Gene:	HP1b / 31834	FlyBaseID:	FBgn0030082	Length:	240	Species:	Drosophila melanogaster
Sequence 2:	NP_001002090.1	Gene:	cbx1b / 415180	ZFINID:	ZDB-GENE-040625-68	Length:	203	Species:	Danio rerio

Alignment Length:	152	Identity:	89/152 - (58%)
Similarity:	107/152 - (70%)	Gaps:	8/152 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 EFSVERVEDKRTVNGRTEYYLKWKGYPRSENTWEPVENLDCPDLIANFEESLKNNKKETKKRLST 67
            |:.||:|.|:|.|.|:.||.|||||:...:|||||.||||||||||.|.:|.|..:...|:|..|
Zfish    47 EYVVEKVLDRRVVKGKVEYLLKWKGFSDEDNTWEPDENLDCPDLIAEFLQSQKTAESGGKRRAET 111

  Fly    68 SSTPESIRSKRKSFLEDDTEEQKKLIGFERGLEASKILGATDSSGHLMFLMKWKGSDHADLVPAK 132
            ....:..: |||       :|.:||.||.|||:..:|:|||||||.||||||||.||.|||||||
Zfish   112 DGDGKETK-KRK-------DEPEKLRGFARGLDPERIIGATDSSGELMFLMKWKNSDEADLVPAK 168

  Fly   133 LANTRCPQVVIQFYEERLTWHT 154
            .||.:||||||.|||||||||:
Zfish   169 EANVKCPQVVISFYEERLTWHS 190

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
HP1b	NP_001162713.1	CHROMO	3..52	CDD:214605	31/48 (65%)
HP1b	NP_001162713.1	Chromo_shadow	100..151	CDD:279701	38/50 (76%)
cbx1b	NP_001002090.1	Chromo	54..97	CDD:278797	27/42 (64%)
cbx1b	NP_001002090.1	Chromo_shadow	136..187	CDD:279701	38/50 (76%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	91	1.000	Domainoid score	I7663
eggNOG	1	0.900	-	-		E1_KOG1911
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H89116
Inparanoid	1	1.050	183	1.000	Inparanoid score	I3949
OMA	1	1.010	-	-		QHG52905
OrthoDB	1	1.010	-	-		D1628171at2759
OrthoFinder	1	1.000	-	-		FOG0000191
OrthoInspector	1	1.000	-	-		otm25057
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X422
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	12	11.840