DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment HP1b and cbx1a

DIOPT Version :9

Sequence 1:	NP_001162713.1	Gene:	HP1b / 31834	FlyBaseID:	FBgn0030082	Length:	240	Species:	Drosophila melanogaster
Sequence 2:	NP_956040.2	Gene:	cbx1a / 326746	ZFINID:	ZDB-GENE-030131-4945	Length:	212	Species:	Danio rerio

Alignment Length:	157	Identity:	88/157 - (56%)
Similarity:	109/157 - (69%)	Gaps:	11/157 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 EFSVERVEDKRTVNGRTEYYLKWKGYPRSENTWEPVENLDCPDLIANF--EESLKNNKKET---K 62
            |:.||:|.|:|.|.||.||.|||||:...:|||||.:|||||||||.:  :..:.::|||:   :
Zfish    49 EYVVEKVLDRRVVKGRVEYLLKWKGFSEEDNTWEPEDNLDCPDLIAEYMTKHKINDDKKESSAKR 113

  Fly    63 KRLSTSSTPESIRSKRKSFLEDDTEEQKKLIGFERGLEASKILGATDSSGHLMFLMKWKGSDHAD 127
            |...|....|..|.|::.      :||.|..||.|||:..:|:|||||||.||||||||.||.||
Zfish   114 KESDTDGGGEDSRPKKRK------DEQDKPRGFARGLDPERIIGATDSSGELMFLMKWKNSDEAD 172

  Fly   128 LVPAKLANTRCPQVVIQFYEERLTWHT 154
            |||||.||.:||||||.|||||||||:
Zfish   173 LVPAKEANVKCPQVVISFYEERLTWHS 199

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
HP1b	NP_001162713.1	CHROMO	3..52	CDD:214605	30/50 (60%)
HP1b	NP_001162713.1	Chromo_shadow	100..151	CDD:279701	38/50 (76%)
cbx1a	NP_956040.2	Chromo	56..96	CDD:278797	26/39 (67%)
cbx1a	NP_956040.2	Chromo_shadow	145..196	CDD:279701	38/50 (76%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	91	1.000	Domainoid score	I7663
eggNOG	1	0.900	-	-		E1_KOG1911
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H89116
Inparanoid	1	1.050	183	1.000	Inparanoid score	I3949
OMA	1	1.010	-	-		QHG52905
OrthoDB	1	1.010	-	-		D1628171at2759
OrthoFinder	1	1.000	-	-		FOG0000191
OrthoInspector	1	1.000	-	-		otm25057
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X422
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	13	12.840