DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment HP1b and hpl-1

DIOPT Version :9

Sequence 1:	NP_001162713.1	Gene:	HP1b / 31834	FlyBaseID:	FBgn0030082	Length:	240	Species:	Drosophila melanogaster
Sequence 2:	NP_510199.1	Gene:	hpl-1 / 181450	WormBaseID:	WBGene00001995	Length:	184	Species:	Caenorhabditis elegans

Alignment Length:	152	Identity:	59/152 - (38%)
Similarity:	82/152 - (53%)	Gaps:	23/152 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 FSVERVEDKRTVNGRTEYYLKWKGYPRSENTWEPVENLDCPDLIANFEESLKNNKKETKKRL--- 65
            |.||:|.:||...|.:|||:||:|:|.||.:|||:|||.|..:|..:|:...  |:.|:||.
Worm    37 FVVEKVLNKRLTRGGSEYYIKWQGFPESECSWEPIENLQCDRMIQEYEKEAA--KRTTRKRRYSP 99

  Fly    66 --STSSTPESIRSKRKSFLEDDTEEQKKLIGFERGLEASKILGATDSSGHLMFLMKWKGSDHADL 128
              ||||:.|         |:..|.::      ..|.....|:|.|.:.|.|.||.|: ..|...|
Worm   100 QPSTSSSAE---------LQPSTSDE------WAGKTLKTIIGITKAPGELHFLCKF-SDDSVHL 148

  Fly   129 VPAKLANTRCPQVVIQFYEERL 150
            :|.:.||.|.|..||:|||.||
Worm   149 IPLREANVRFPSQVIKFYETRL 170

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
HP1b	NP_001162713.1	CHROMO	3..52	CDD:214605	24/47 (51%)
HP1b	NP_001162713.1	Chromo_shadow	100..151	CDD:279701	22/51 (43%)
hpl-1	NP_510199.1	CD_HP1_like	36..85	CDD:349316	24/47 (51%)
hpl-1	NP_510199.1	ChSh	114..174	CDD:197638	23/64 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160161955
Domainoid	1	1.000	66	1.000	Domainoid score	I6523
eggNOG	1	0.900	-	-		E1_KOG1911
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	95	1.000	Inparanoid score	I3624
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1628171at2759
OrthoFinder	1	1.000	-	-		FOG0000191
OrthoInspector	1	1.000	-	-		mtm4828
orthoMCL	1	0.900	-	-		OOG6_104220
Panther	1	1.100	-	-	LDO	PTHR22812
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R8954
SonicParanoid	1	1.000	-	-		X422
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.790