DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment HP1b and cec-1

DIOPT Version :9

Sequence 1:	NP_001162713.1	Gene:	HP1b / 31834	FlyBaseID:	FBgn0030082	Length:	240	Species:	Drosophila melanogaster
Sequence 2:	NP_498862.1	Gene:	cec-1 / 176190	WormBaseID:	WBGene00000414	Length:	304	Species:	Caenorhabditis elegans

Alignment Length:	274	Identity:	53/274 - (19%)
Similarity:	92/274 - (33%)	Gaps:	112/274 - (40%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 FSVERVEDKRTVNGRTEYYLKWKGYPRSENTWEPVENLDCPDLIANF--------------EESL 54
            ::||.:.:.|...|::|:|:||.||..:.|:|||.||:..|.||..|              ::.:
Worm     8 YTVESILEHRKKKGKSEFYIKWLGYDHTHNSWEPKENIVDPTLIEAFFTREAARKAEIKAKKDKM 72

  Fly    55 KNNKKETKKRLSTS------ST------------PESIRSKRKSFL------EDDTEEQKKLIGF 95
            ...||....:.|.|      ||            |:....||:...      :.||:|:..
Worm    73 AAGKKGASSKASASVSKASASTPARGAKAAPKPPPKKSPPKRQRLAGGDIRPDSDTDEEHS---- 133

  Fly    96 ERGLEASKILGATDSSGHLMFLMKWKGSDHADLVPAKLANTRCPQVVIQFYEERLTWHTGSGNGN 160
                .|.|...|.|..         :..|..:.||.|      .:.|.:..||.
Worm   134 ----SADKKSKAEDEE---------EVEDDEEPVPKK------KKEVQEEPEEE----------- 168

  Fly   161 GNTNSVNLGSSGGLGSVGGSGAGDDTAPGSVGTTGGGSNIDGGDEEDPEPASPIGSINQDENIKP 225
                                                 .:::|.|||:   :..:..:.:||.::.
Worm   169 -------------------------------------ESVEGEDEEE---SQEVEDLKEDEKMEE 193

  Fly   226 DESSELDNGQPDAD 239
            ||..|.::.|.:::
Worm   194 DEKEEEEDVQLESE 207

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
HP1b	NP_001162713.1	CHROMO	3..52	CDD:214605	20/61 (33%)
HP1b	NP_001162713.1	Chromo_shadow	100..151	CDD:279701	11/50 (22%)
cec-1	NP_498862.1	CHROMO	8..59	CDD:214605	20/50 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1628171at2759
OrthoFinder	1	1.000	-	-		FOG0000191
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X422
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.920