Protein Alignment HP1b and CBX1

DIOPT Version :10

• Sequence 1: NP_572521.2
• Gene: HP1b / 31834
• FlyBaseID: FBgn0030082
• Length: 240
• Species: Drosophila melanogaster
• Sequence 2: NP_006798.1
• Gene: CBX1 / 10951
• HGNCID: 1551
• Length: 185
• Species: Homo sapiens
• Alignment Length: 159
• Identity: 92/159 - (57%)
• Similarity: 109/159 - (68%)
• Gaps: 13/159 - (8%)

  Fly     3 EFSVERVEDKRTVNGRTEYYLKWKGYPRSENTWEPVENLDCPDLIANFEESLK----NNKKETKK 63
            |:.||:|.|:|.|.|:.||.|||||:...:|||||.||||||||||.|.:|.|    .:|.|..|
Human    20 EYVVEKVLDRRVVKGKVEYLLKWKGFSDEDNTWEPEENLDCPDLIAEFLQSQKTAHETDKSEGGK 84

  Fly    64 RLSTSSTP---ESIRSKRKSFLEDDTEEQKKLIGFERGLEASKILGATDSSGHLMFLMKWKGSDH 125
            |.:.|.:.   |..:.|:|.      ||.:|..||.||||..:|:|||||||.||||||||.||.
Human    85 RKADSDSEDKGEESKPKKKK------EESEKPRGFARGLEPERIIGATDSSGELMFLMKWKNSDE 143

  Fly   126 ADLVPAKLANTRCPQVVIQFYEERLTWHT 154
            |||||||.||.:||||||.|||||||||:
Human   144 ADLVPAKEANVKCPQVVISFYEERLTWHS 172

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HP1b	NP_572521.2	CD_HP1_like	3..52	CDD:349281	31/48 (65%)
		CSD	99..150	CDD:349275	39/50 (78%)
CBX1	NP_006798.1	CD_HP1beta_Cbx1	20..69	CDD:349297	31/48 (65%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	63..124		24/66 (36%)
		CSD_HP1beta_Cbx1	112..169	CDD:349301	44/56 (79%)